LIFE SCIENCES

BY WILLIAM P. LOOMIS
Department of Biology
University of California, San Diego
La Jolla, Calif.

" Bidirectional replication of circular chromosomes in Eseherichia coil stops at orientation-dependent sequences. A protein, tus, recognizes these 21-23 base pair terminators.

T. Hill, A. Pelletier, M. Tecklenburg, P. Kuempel, “Identification of the DNA sequence from theE. coil terminus region that halts replication forks,” Cell, 55 (3), 459-66,4 November 1988.

M. Hidaka, M. Akiyama, T. Horiuchi, “A consensus sequence of three DNA replication terminus sites on theE. coli chromosome is highly homologous to the terR sites of the R6K plasmid,” Cell, 55 (3), 487-75,4 November 1988.

" A deletion that reduces the amount of the histones H2A and H2B in yeast results in alteration of chromatin structure near some genes but not others.

D. Norris, B. Dunn, M. Osley, “The effect of histone gene deletions on chromatin structure in...

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