Notable

J.O. Korbel et al., "SHOT: A Web server for the construction of genome phylogenies," Trends in Genetics, 18[3]:158-62, March 1, 2002. "This paper reports the results of phylogenetic analysis using whole genome comparisons and introduces a new Web server (named "SHOT") for further analysis by gene-content and gene-order methods. Among the results, the gene-content method showed Homo sapiens to be more closely related to Drosophila melanogaster than Caenorhabditis elegans, and both methods showed

Jeffrey Perkel
May 12, 2002
J.O. Korbel et al., "SHOT: A Web server for the construction of genome phylogenies," Trends in Genetics, 18[3]:158-62, March 1, 2002.

"This paper reports the results of phylogenetic analysis using whole genome comparisons and introduces a new Web server (named "SHOT") for further analysis by gene-content and gene-order methods. Among the results, the gene-content method showed Homo sapiens to be more closely related to Drosophila melanogaster than Caenorhabditis elegans, and both methods showed Halobacterium sp. to branch at the root of the Archaea."
—Shiladitya DasSarma,
University of Maryland
Biotechnology Institute, US

Membrane-Associated Proteins

Y. Fang et al., "Membrane protein microarrays," Journal of the American Chemical Society, 124[11]:2394-5, March 20, 2002.

"Almost half of all known drug targets are membrane-associated proteins, but there had been no efficient high throughput microarray assays developed for membrane proteins until the process reported in this paper. The authors...