Notable

T. Sicheritz-Pontén, S.G. Andersson, "A phylogenomic approach to microbial evolution," Nucleic Acids Research, 29[2]:545-52, Jan. 15, 2001. F1000 Rating: Must Read "The paper describes methods and computer programs for automated phylogenetic analysis of complete genome datasets, as well as useful visualization tools for the results. The tools should be useful to those looking for genes that may have unusual evolutionary histories relative to other genes in the same genome." —Jonath

Jeffrey Perkel
Jan 20, 2002
T. Sicheritz-Pontén, S.G. Andersson, "A phylogenomic approach to microbial evolution," Nucleic Acids Research, 29[2]:545-52, Jan. 15, 2001.


F1000 Rating: Must Read

"The paper describes methods and computer programs for automated phylogenetic analysis of complete genome datasets, as well as useful visualization tools for the results. The tools should be useful to those looking for genes that may have unusual evolutionary histories relative to other genes in the same genome."
—Jonathan A. Eisen,
The Institute for Genomic Research (TIGR), US

Structural Biology

J.E. Barrick et al., "Large libraries reveal diverse solutions to an RNA recognition problem," Proceedings of the National Academy of Sciences (PNAS), 98[22]: 12374-8, Oct. 23, 2001.

F1000 Rating: Recommended

"The development of tight-binding and highly selective small molecule ligands for RNA remains a very challenging problem, but this article demonstrates that combinatorial selection approaches such as the in vitro mRNA-peptide fusion systems...

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