Protein-based Inheritance
© Cell PressA transmission electron micrograph of Sup35 protein that has formed amyloid fibers from its prion structure Though mounting evidence points to prions as the infectious element in diseases such as scrapie and Creutzfeldt-Jakob (CJD), direct proof is missing. A prion has the same amino acid sequence as the normal protein, but it has an altered structural form. The protein-only hypothesis states that a prion can cause disease and also spread it without transmitting any genetic mate
Mar 5, 2000
© Cell Press |
![]() A transmission electron micrograph of Sup35 protein that has formed amyloid fibers from its prion structure |
Prions in Yeast
Yeast prions, unlike their mammalian counterpart, do not kill the...
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