Research Notes
Methylation as a Cancer Switch Courtesy of Richard Roberts, New England BiolabsReaction model: Methyltransferase (white) is methylating cyclic carbon 5 of a cytosine nucleotide. The tenuous link between cancer and epigenetic changes, changes in gene expression without DNA mutations, has been strengthened by Joe Costello, assistant professor at the University of California, San Francisco, and colleagues (J.F. Costello et al., "Aberrant CpG-island methylation has non-random and tumour-type-specifi
Feb 20, 2000
Methylation as a Cancer Switch
Courtesy of Richard Roberts, New England Biolabs |
![]() Reaction model: Methyltransferase (white) is methylating cyclic carbon 5 of a cytosine nucleotide. |
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