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Unraveling The Biochemistry of Fat Metabolism

Biochemical InterestBelieved MechanismPotential Drug Leptin receptorWhen mutated, resists leptin bindingRepairs receptor; creates tailored leptin-like molecule Neuropeptide YStimulates carbohydrate cravingNPY antagonist GalaninStimulates fat intake and lowers insulin levelGalanin antagonist CholecystokininSignals brain to stop eatingCCK agonist DopamineSignals brain to stop eatingDopamine/fatty acid combination drug

The Scientist Staff

Biochemical InterestBelieved MechanismPotential Drug
Leptin receptorWhen mutated, resists leptin bindingRepairs receptor; creates tailored leptin-like molecule
Neuropeptide YStimulates carbohydrate cravingNPY antagonist
GalaninStimulates fat intake and lowers insulin levelGalanin antagonist
CholecystokininSignals brain to stop eatingCCK agonist
DopamineSignals brain to stop eatingDopamine/fatty acid combination drug

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