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Yes, Biologically Speaking, Sex Does Matter

Editor's Note: This is the first article in a series on sex-based differences in the biology of males and females, a topic that has gained momentum over the last decade. Subsequent articles will cover sex-based differences in brain structure and strokes, genetics, autoimmunity, and drug metabolism. Lisa Damiani When I was a kid, I always wanted to know why there were two sexes," recalls Florence Haseltine, director of the Center for Population Research at the National Institute of Child Health

Karen Young Kreeger
Editor's Note: This is the first article in a series on sex-based differences in the biology of males and females, a topic that has gained momentum over the last decade. Subsequent articles will cover sex-based differences in brain structure and strokes, genetics, autoimmunity, and drug metabolism.
Lisa Damiani


When I was a kid, I always wanted to know why there were two sexes," recalls Florence Haseltine, director of the Center for Population Research at the National Institute of Child Health and Human Development. "From the time I was 4, I used to drive my father crazy. He said, 'Well, when you grow up, you figure it out.'"

Haseltine, who has devoted much of her career to pursuing such questions, was heartened last April when the Institute of Medicine validated this budding area of investigation by issuing its report, "Exploring the Biological Contributions to Human Health: Does Sex Matter?"1...

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