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Opinion: Biomarkers of Longevity Not Ready for the Clinic
Opinion: Biomarkers of Longevity Not Ready for the Clinic
John D. Loike and Ruth L. Fischbach | Sep 27, 2019
The science isn’t there yet, nor are the known interventions that ought to be combined with delivering such predictions.
Opinion: Develop Organoids, Not Chimeras, for Transplantation
Opinion: Develop Organoids, Not Chimeras, for Transplantation
John D. Loike and Robert Pollack | Oct 1, 2019
Scientists are devising human-animal hybrids for harvesting human organs, but lab-derived mini-organs are a less ethically fraught solution to meeting the need for transplantation.
Opinion: Develop Organoids, Not Chimeras, for Transplantation
Opinion: Develop Organoids, Not Chimeras, for Transplantation
John D. Loike, Robert Pollack | Aug 23, 2019
Scientists are devising human-animal hybrids for harvesting human organs, but lab-derived mini-organs are a less ethically fraught solution to meeting the need for transplantation.
Opinion: Test Brain-Reviving Technology in Infants First
Opinion: Test Brain-Reviving Technology in Infants First
John D. Loike, Alan Kadish | Jul 9, 2019
If a system tested in decapitated pigs ever gets to human clinical trials, neuroscientific and ethical reasons point to testing babies before adults.
The Human Brain: Blessing and Curse
The Human Brain: Blessing and Curse
Bob Grant | Oct 1, 2019
Our brains are mysterious, fragile, and mischievous. That’s what makes them fascinating.
Opinion: How to Define Life
Opinion: How to Define Life
John D. Loike, Robert Pollack | May 2, 2019
As artificial life forms become more sophisticated, we propose a simple list of criteria to determine whether synthetic biological organisms and robots are living beings.
Opinion: Ethical Challenges in Using iPS Cells to Treat Paralysis
Opinion: Ethical Challenges in Using iPS Cells to Treat Paralysis
John D. Loike, Martin Grumet | Mar 7, 2019
Uncertainties about the cells’ risk profiles and the potential for hyping unproven therapies mean scientists and the media must tread carefully.
Opinion: Ethical Boundaries Needed on the Uses of Synthetic DNA
Opinion: Ethical Boundaries Needed on the Uses of Synthetic DNA
John D. Loike, Robert Pollack | Mar 1, 2019
A newly expanded genetic alphabet that includes four synthetic nucleotides highlights the need for strict boundaries on their use.
Opinion: Don’t Ban the Use of CRISPR in Embryos
Opinion: Don’t Ban the Use of CRISPR in Embryos
John D. Loike | Nov 29, 2018
Despite a premature and ethically sketchy claim of genome editing in twin girls, an outright prohibition could blunt promising, responsible progress.
Opinion: The Central Dogma of Mitochondrial Genetics Needs Rewriting
Opinion: The Central Dogma of Mitochondrial Genetics Needs Rewriting
John D. Loike | Dec 12, 2018
The recent discovery of 17 people who have inherited maternal and paternal lines of mitochondrial DNA has major ramifications for medical and ancestry research.

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