ImClone Systems' SoHo headquarters

ImClone Systems began its history as a New York company in 1984 when its founders, an immunologist and a pathologist both living and working in the city, set out to meld the established and respected world of New York City academia with the dynamic and fledgling biotechnology industry. Two short years after its incorporation, with a staff of 12 employees and some venture capital funding, ImClone Systems opened its laboratories in downtown New York's SoHo neighborhood in a space that formerly served as a shoe factory.

ImClone Systems got its name from the three scientific areas its founders had originally intended the company to pursue: immunology, gene cloning, and information systems for the life sciences industry. The company's first Food & Drug Administration-approved products were diagnostic kits used in immunology, but it also pursued several infectious disease and cancer vaccine research programs.

These early endeavors led...

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