Uncovering Leprosy’s Genetic Recipe for Success
Uncovering Leprosy’s Genetic Recipe for Success
Nele Haelterman, PhD | Aug 17, 2022
Researchers identify what makes certain people more likely to contract leprosy than others.
GENETIC PREDISPOSITION TO VITAMIN D DEFICIENCY CONTRIBUTES TO SEVERE COVID-19
Genetic Predisposition to Vitamin D Deficiency Contributes to Severe COVID-19
Iris Kulbatski, PhD | Aug 15, 2022
Ana Teresa Freitas discusses how individual variation in vitamin D synthesis and metabolism influences susceptibility to upper respiratory viruses.
Mini organs in a dish
Brush Up: What Are Organoids and How Are They Made?
Jennifer Zieba, PhD | Aug 11, 2022
Miniaturized, in vitro versions of organs provide insights into disease and development.
Time Traveling Mini-Brains on a Mission to Conquer Space
Time Traveling Mini-Brains on a Mission to Conquer Space
Iris Kulbatski, PhD | Aug 11, 2022
Alysson R. Muotri discusses his launch of brain organoids into outer space and how microgravity enriches our understanding of brain development and disease.
in love with the shape of you
In Love with the Shape of You: Physical Scaffolding Defines Organoid Patterning
Sejal Davla, PhD | Aug 8, 2022
Controlling a growing tissue’s shape achieves deterministic and uniform patterning in intestinal organoids.
COVID-19 vaccine vials
COVID-19 Vaccines Induce Better Long-Term Immunity than Infection
Jennifer Zieba, PhD | Aug 8, 2022
For the first time, researchers performed a head-to head longitudinal study comparing the immune response elicited by mRNA and traditional COVID-19 vaccines to primary infections.
An abstract stained-glass portrait of a woman with an image of an eye representing the brain
Through the Looking Glass: Aging, Inflammation, and Gut Rejuvenation
Iris Kulbatski, PhD | Aug 8, 2022
Renewing the aging gut microbiome holds promise for preventing inflammatory brain and eye degeneration.
Motor neurons, undergoing degeneration in ALS
Mutant T Cells That Drive Amyotrophic Lateral Sclerosis (ALS) Progression May React To a Brain Antigen
Nele Haelterman, PhD | Aug 8, 2022
Scientists discovered a possibly autoreactive T cell population that forecasts and supports disease progression.
The balance of mind and body on a seesaw
Psychological Stress Distracts the Immune System from Fighting Infections
Jennifer Zieba, PhD | Aug 8, 2022
Acute stress makes immune cells migrate immediately to the bone marrow, which prepares the body for injury at the expense of increasing infectious disease susceptibility.
 somite organoid in culture
Reconstructing How the Spine Takes its Shape
Nele Haelterman, PhD | Aug 5, 2022
Marina Sanaki-Matsumiya figured out how to grow human somites in a dish through a process that mirrors the tissue’s development in the embryo.
Two babies engaged in conversation, with one shouting in the other’s ear
Nurturing Early Language Skills Prevents the Behavioral Expression of a Genetic Trait
Iris Kulbatski, PhD | Jul 11, 2022
A new precision medicine approach is making life sweeter for infants unable to metabolize milk sugar.
3d illustration proteins with lymphocytes , t cells or cancer cells
New Patient Tumor Cell Models Rapidly Predict Cancer Therapy Outcomes
Jennifer Zieba, PhD | Jul 11, 2022
A new benchtop microfluidic device generates patient-derived tumor micro-organospheres that allow for real-time cancer therapy decisions.
spatial CRISPR screen for cancer
A Brave New World for Spatial Genomics in Cancer Research
Nele Haelterman, PhD | Jun 27, 2022
A new CRISPR screening technology allows scientists to recreate tumor heterogeneity in vivo and study how it affects all aspects of cancer biology.
3-D image of a tumor
Cancer Cells Go Incognito to Cause Therapy Relapse
Niki Spahich, PhD | Jun 27, 2022
Dormant cancer cells and dysfunctional immune cells living together in a tumor niche form a therapy-resistant reservoir.
Exploring how spatial relationships drive heart function
Mapping Out What Makes the Heart Tick
Nathan Ni, PhD | Jun 27, 2022
A novel atlas reveals region-specific links between structural, mechanical, and genetic properties within the heart.
Setting High Standards for Antibody Production Using Nucleosomes
Setting High Standards for Antibody Production Using Nucleosomes
Fortis Life Sciences | Jun 20, 2022
A unique approach to antibody production that exposes antibody candidates to nucleosomes is revolutionizing best practices.
Raising the Bar for Biomarkers and Early Diagnostics in Neurodegenerative Disease
Raising the Bar for Biomarkers and Early Diagnostics in Neurodegenerative Disease
Fortis Life Sciences | Jun 20, 2022
Identifying novel biomarkers of Parkinson’s disease enables early diagnosis and treatment monitoring.
Reinvigorating the Immune System to Attack Cancer Cells Using Highly Specific Antibodies
Reinvigorating the Immune System to Attack Cancer Cells Using Highly Specific Antibodies
Fortis Life Sciences | Jun 20, 2022
Cancer immunotherapy targets the tumor microenvironment, blocking the molecular pathways that tumors exploit to prevent immune cell activity.
Muscle immobilization leads to atrophy
Antioxidants Put the Pep Back in One’s Step
Niki Spahich, PhD | Jun 13, 2022
Delivering antioxidants via extracellular vesicles to atrophied muscles restores them during rehabilitation.
Researchers are applying mechanical force to bone cells grown on apple scaffolds to mimic the affect of gravity on bone regeneration.
Apples Lay the Foundation for Regenerating Bone
Iris Kulbatski, PhD | May 9, 2022
Researchers use innovative plant-based biomaterials to grow new bone for restoring depleted bone mass after space travel.