Researchers are applying mechanical force to bone cells grown on apple scaffolds to mimic the affect of gravity on bone regeneration.
Apples Lay the Foundation for Regenerating Bone
Iris Kulbatski, PhD | May 9, 2022
Researchers use innovative plant-based biomaterials to grow new bone for restoring depleted bone mass after space travel.
Don Ingber engineered cystic fibrosis airway chips that recapitulate patient symptoms.
A New Model of Lung Disease Paves the Way for Personalized Treatments
Nele Haelterman, PhD | May 9, 2022
Scientists engineered a lung-on-a-chip model from patient cells that mimics cystic fibrosis.
Meat sample in open disposable plastic cell culture dish in modern laboratory or production facility.
Removing the Animals from Lab-Grown Meat
Niki Spahich, PhD | May 9, 2022
Growing meat in a laboratory may seem like science fiction, but researchers around the world are perfecting the culture of animal muscle intended for human consumption.
Dogs under blanket together stock photo
A Nose by Any Other Name: Tracking the Scent of Tumor Metabolic Waste
Iris Kulbatski, PhD | Apr 11, 2022
The unique odor profiles of tumors can be used to develop diagnostic sensing tools.
Abstract Genetics Disease stock photo
Bridging Disciplines to Study CRISPR-Induced Chromosome Destabilization
Aparna Nathan | Apr 8, 2022
A collaboration between friends led to a cautionary finding about CRISPR’s effect on cells.
Engineered Bacteria Make Tumors More T Cell-Friendly
Engineered Bacteria Make Tumors More T Cell-Friendly
Aparna Nathan | Apr 8, 2022
Microbes designed to produce specific immunomodulatory metabolites could give immunotherapy a boost.
Female reproductive System Anatomy stock photo
Cells in the Ovary are Responsive Shape-Shifters
Roni Dengler, PhD | Apr 8, 2022
Rounds of trial-and-error exploring the layer of cells covering the ovary leave open questions about stem cells that are associated with ovarian cancer.
3D virus cells attacking a DNA strand
HIV DNA Circularizes to Bypass CRISPR-Based Treatments
Nele Haelterman, PhD | Mar 7, 2022
CRISPR-mediated removal of HIV can create small, infectious DNA molecules.
Salmonella living within macrophages can survive antibiotic treatment and potentially give rise to resistance by two different mechanisms that slow or arrest their growth.
Bacteria Go Dormant to Survive Antibiotics and Restart Infections
Niki Spahich, PhD | Mar 7, 2022
In Salmonella, two seemingly similar antibiotic survival strategies result from very different molecular mechanisms.
Researchers use bacterial whole genome sequencing to compare the phylogenetic relationship between environmental and clinical samples.
Aquatic Bacteria Reveal a Common Genetic Link to a Deadly Human Pathogen
Iris Kulbatski, PhD | Mar 7, 2022
Researchers use genetic clues to track the spread of antibiotic resistant bacteria from the environment to patients.
Researchers target E. coli in the mouse gut
Modifying the Microbiome In Vivo, One Species or Gene at a Time
Niki Spahich, PhD | Feb 16, 2022
To manipulate the microbiome, researchers engineered a CRISPR delivery system that precisely targets bacteria in the mouse gut.
Human cell
How Soft or Stiff Substrates Direct Stem Cell Differentiation
Roni Dengler, PhD | Feb 7, 2022
Mechanical signals point mesenchymal stem cells down a particular differentiation path, but not all cells follow the lead.
Stem Cells in Human Teeth Follow the Rules of Their Environment
Roni Dengler, PhD | Feb 7, 2022
How stem cells in human teeth respond to different environmental conditions offers clues for regenerative medicine.
Stem Cell Transplant Treats Parkinson’s Disease in Monkeys
Roni Dengler, PhD | Feb 7, 2022
Personalized stem cells improved motor symptoms and depression signs in monkeys modeling Parkinson’s disease, paving the way for trials in human patients.
Maternal smoking during pregnancy alters placental function and fetal growth
Roni Dengler, PhD | Feb 3, 2022
Smoking during pregnancy changes marks on placental DNA, altering its responses to environmental stressors.
Antibiotics May Influence Brain Development
Antibiotics May Influence Brain Development
Roni Dengler, PhD | Jan 10, 2022
Low doses of continuous penicillin exposure altered mouse pups’ microbiomes and gene expression in brain areas associated with emotional and cognitive function.
Mummified Gut Bugs Reveal Ancient Dietary Secrets
Mummified Gut Bugs Reveal Ancient Dietary Secrets
Iris Kulbatski, PhD | Jan 10, 2022
Reconstructing the diet and microbiome of human ancestors shows an astonishingly rapid loss of microbiome diversity.
Erika More developed a jello-like tissue system to study how immune cells stimulate tissues and blood vessel growth.
An Engineer’s Perspective on Autoimmunity
Aparna Nathan | Dec 10, 2021
Erika Moore builds biomaterials to study disparate lupus outcomes.
Christmas background
Helping the Immune System Keep its Cool
Aparna Nathan | Dec 10, 2021
Researchers found that lowering the temperature alleviates autoimmunity in mice.
Antibodies in breastmilk from SARS-CoV-2 infection or mRNA vaccination neutralize the virus.
Antibodies Against SARS-CoV-2 in Breast Milk Differ Between Vaccinated and Infected Mothers
Roni Dengler, PhD | Dec 6, 2021
All antibodies against SARS-CoV-2 found in breast milk neutralized the virus.