A 3-D Tumor Microenvironment for Personalized Immunotherapy
A 3-D Tumor Microenvironment for Personalized Immunotherapy
Roni Dengler, PhD | Sep 10, 2021
A new platform enables screening a wide range of combination anticancer therapeutics in a matter of days, which may translate to personalized therapeutic regimens for patients in less time.
A New Model with Fully Functioning Blood Vessels Mimics Brain Cancer
A New Model with Fully Functioning Blood Vessels Mimics Brain Cancer
Roni Dengler, PhD | Sep 10, 2021
A newly developed platform may one day replace cell culture and animal models to personalize cancer treatment.
Heating Up CAR T Cells for Cancer Therapy
Heating Up CAR T Cells for Cancer Therapy
Roni Dengler, PhD | Sep 10, 2021
Heated gold nanoparticles unleash the therapeutic activity of engineered CAR T cells.
Fecal Transplant Restores Youth to Old Mice
Fecal Transplant Restores Youth to Old Mice
Roni Dengler, PhD | Aug 30, 2021
Microbiota from young mice reversed some aspects of aging and enhanced brain health in aged mice.
Gut Bugs May Help Centenarians Reach Their 100th Birthdays
Gut Bugs May Help Centenarians Reach Their 100th Birthdays
Roni Dengler, PhD | Aug 30, 2021
Centenarians have distinct microbiomes with species that produce unique bile acids, which may help thwart illness.
Engineered Yeast Robots Destroy Inflammatory Molecules in an IBD Mouse Model
Engineered Yeast Robots Destroy Inflammatory Molecules in an IBD Mouse Model
Roni Dengler, PhD | Aug 16, 2021
Scientists added a gene circuit that senses and neutralizes proinflammatory ATP to yeast, taking another step towards precision medicine.
Could a Synthetic Probiotic Replace a Strict Diet for Patients with Phenylketonuria?
Could a Synthetic Probiotic Replace a Strict Diet for Patients with Phenylketonuria?
Roni Dengler, PhD | Aug 16, 2021
Synthetic biologists introduced an engineered microbe that may lead to new treatment options for phenylketonuria.
A New COVID-19 Spit Test Is as Easy as 1-2-3
A New COVID-19 Spit Test Is as Easy as 1-2-3
Roni Dengler, PhD | Aug 16, 2021
A device smaller than two stacked decks of cards can reliably detect and discriminate between SARS-CoV-2 variants in spit in less than an hour with results that glow.
How to Grow a Mouse Embryo in a Dish
How to Grow a Mouse Embryo in a Dish
Roni Dengler, PhD | Aug 3, 2021
Researchers are taking the concept of three-dimensional cell culture beyond single organoids to develop embryos from cells.
Organoid Shape Identifies Potential Cancer Drugs
Organoid Shape Identifies Potential Cancer Drugs
Roni Dengler, PhD | Aug 3, 2021
An unusual drug screen takes advantage of “porcupine-like” structures of cancer cells in 3D organoids.
AI Helps Predict Winners and Losers in Clinical Trials
AI Helps Predict Winners and Losers in Clinical Trials
Roni Dengler, PhD | Aug 3, 2021
Pradipta Ghosh has plans to revolutionize the drug discovery pipeline.
Undone Proteins Take Out Bladder Cancer
Undone Proteins Take Out Bladder Cancer
Roni Dengler, PhD | Jul 20, 2021
An unfolded protein found in human milk shows promise in early clinical trials to treat bladder cancer.
Homing Technology Delivers Therapy to Cancerous Bone
Homing Technology Delivers Therapy to Cancerous Bone
Roni Dengler, PhD | Jul 19, 2021
A clever approach to modifying already existing cancer therapies may be a game changer for treating metastatic breast cancer.
Of Guidelines and Gatekeepers: Reproducibility in Flow Cytometry
Of Guidelines and Gatekeepers: Reproducibility in Flow Cytometry
The Scientist Creative Services Team in collaboration with Beckman Coulter Life Sciences | Jul 19, 2021
Guidelines and built-in safeguards ensure the reproducibility of flow cytometry data.
Analyzing Biological Systems with Flow Cytometry
Analyzing Biological Systems with Flow Cytometry
The Scientist Creative Services Team in collaboration with Beckman Coulter Life Sciences | Jul 19, 2021
Single-cell analysis provides a superior view of heterogeneous cell populations.
Antibiotic-Linked Antibody Attacks Cancer’s Sinister Neighbor Cells
Antibiotic-Linked Antibody Attacks Cancer’s Sinister Neighbor Cells
Roni Dengler, PhD | Jul 14, 2021
An unexpected and unprecedented finding may lead to improved cancer therapies.
Glucometers Detect SARS-CoV-2 Infection Within an Hour
Glucometers Detect SARS-CoV-2 Infection Within an Hour
Roni Dengler, PhD | Jun 14, 2021
Glucometers are easy-to-use, cheap, and highly scalable. And they are 100 percent accurate at detecting SARS-CoV-2.
Inhaled Antibody Fragments Protect Infected Animals Against COVID-19
Inhaled Antibody Fragments Protect Infected Animals Against COVID-19
Roni Dengler, PhD | Jun 14, 2021
Tiny but powerful nanobodies may be the innovation that snuffs out the pandemic.
Skin Rash May Point to SARS-CoV-2 Infection
Skin Rash May Point to SARS-CoV-2 Infection
Roni Dengler, PhD | Jun 14, 2021
Skin symptoms are often the first, or only, symptom of COVID-19.
CAR T Cells Derived from Stem Cells Target HIV Tissue Reservoirs in Monkeys
CAR T Cells Derived from Stem Cells Target HIV Tissue Reservoirs in Monkeys
Berly McCoy, PhD | May 25, 2021
Transplanted CAR stem cells persisted long term and showed multilineage engraftment in tissues that harbor HIV.