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Researchers identify what makes certain people more likely to contract leprosy than others.

Ana Teresa Freitas discusses how individual variation in vitamin D synthesis and metabolism influences susceptibility to upper respiratory viruses.

Miniaturized, in vitro versions of organs provide insights into disease and development.

Alysson R. Muotri discusses his launch of brain organoids into outer space and how microgravity enriches our understanding of brain development and disease.

Controlling a growing tissue’s shape achieves deterministic and uniform patterning in intestinal organoids.

For the first time, researchers performed a head-to head longitudinal study comparing the immune response elicited by mRNA and traditional COVID-19 vaccines to primary infections.

Renewing the aging gut microbiome holds promise for preventing inflammatory brain and eye degeneration.

Scientists discovered a possibly autoreactive T cell population that forecasts and supports disease progression.

Acute stress makes immune cells migrate immediately to the bone marrow, which prepares the body for injury at the expense of increasing infectious disease susceptibility.

Marina Sanaki-Matsumiya figured out how to grow human somites in a dish through a process that mirrors the tissue’s development in the embryo.

A new precision medicine approach is making life sweeter for infants unable to metabolize milk sugar.

A new benchtop microfluidic device generates patient-derived tumor micro-organospheres that allow for real-time cancer therapy decisions.

A new CRISPR screening technology allows scientists to recreate tumor heterogeneity in vivo and study how it affects all aspects of cancer biology.

Dormant cancer cells and dysfunctional immune cells living together in a tumor niche form a therapy-resistant reservoir.

A novel atlas reveals region-specific links between structural, mechanical, and genetic properties within the heart.

A unique approach to antibody production that exposes antibody candidates to nucleosomes is revolutionizing best practices.

Identifying novel biomarkers of Parkinson’s disease enables early diagnosis and treatment monitoring.

Cancer immunotherapy targets the tumor microenvironment, blocking the molecular pathways that tumors exploit to prevent immune cell activity.

Delivering antioxidants via extracellular vesicles to atrophied muscles restores them during rehabilitation.

Researchers use innovative plant-based biomaterials to grow new bone for restoring depleted bone mass after space travel.