Post-translational modifications (PTMs) play a key role in dynamic cellular processes, regulating gene expression, protein activity, localization, and degradation, as well as protein interaction. Modification-specific antibodies offer a versatile tool for the characterization of post-translational modifications.
About Rockland Immunochemicals Inc.
Rockland Immunochemicals, Inc. offers each academic, biopharma, and diagnostic professional thousands of antibodies with the aim of providing the right antibody that is the perfect fit for every occasion. No matter the context—basic research to disease therapy, phosphorylated to methylated and beyond—Rockland embraces the challenge to design, produce, validate, and deliver the absolute best antibodies and life science reagents available in the market today and every day. Post-translational changes alter the structure of individual proteins, and therefore potentially affect their activity, stability, localization and/or interacting partner molecules.
Antibodies are arguably the most prevalent and valuable tool for tracking these changes. Rockland has developed and perfected a process for manufacturing antibodies to detect Post-Translational Modifications (PTM) that has been in use for over a decade. In the process, modification-specific antibodies are prepared using synthetic modified peptides. The trouble is that antibodies recognizing nonphosphorylated forms must be excluded —a skill that Rockland has delicately mastered through years of experience. To ensure the integrity of these sensitive antibodies, Rockland performs quality control testing on every lot to guarantee antibodies function in the intended assays. All work is performed in Rockland’s laboratories, located just outside of Philadelphia, PA.
For over fifty years, we at Rockland have assembled an outstanding team of scientists and technicians with a singular dedication to making great antibodies fit for the exacting needs of scientific discovery. From start to finish, we think, innovate, refine, troubleshoot, deliberate, hone, solve, synthesize, purify, conjugate, digest, quantify, qualify, test, package, ship, and guarantee. As we manufacture and validate your antibody, whether selected from our catalog or custom-made, we are keen and intent to deliver reproducible and reliable results in your assay. By ensuring that each step of the process can be certified and validated multiple times, we can achieve our goal to provide accountability and repeatable test results with each antibody we develop. Protect your experiments with Rockland antibodies.
Download this poster sponsored by Rockland Immunochemicals Inc., to learn how you can choose the best high-affinity, high specificity antibody for your PTM detection needs.