MilliporeSigma: Dialfiltration vs. Dialysis

Diafiltration and dialysis can be used to exchange buffer in different ways. Learn more about when to use each in the video below.

Nov 21, 2019
The Scientist Creative Services Team

Dialysis is the passive removal of solutes using a semipermeable membrane whereas dialfiltration is the forced exchange of buffer using pressure. Diafiltration also concentrates samples, but it isn't suitable for every sample. To learn more, visit