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R&D Systems: Types of Biotinylated Proteins

Examine the differences between different types of biotinylated proteins to pick the right one for your assay!

The Scientist Creative Services Team

Jan 21, 2020

Biotinylated proteins are popularly used in antibody-based laboratory assays. Compare and contrast the different strengths of R&D Systems amine- and Avi-tag-labeled biotinylated proteins with this video!

Medical Researcher and Philanthropist Laszlo Bito Dies at 87

In Editing RNA, Researchers See Endless Possibilities

PATH TO TREATMENT: Marley, pictured here with her father, was diagnosed with the rare genetic condition Bachmann-Bupp syndrome a few years ago.

Doctors Treat Girl’s Genetic Disorder with Repurposed Drug

Infographic showing endogenous adenosine enzymes acting on RNA (ADARs) edit genetic material in the cell by attaching to naturally occurring double-stranded RNAs, including mRNAs, and switching out A bases with I bases (left). Therapeutic RNA editing platforms based on this mechanism fall into one of two categories: either they use engineered enzymes, which generally consist of the editing part of the ADAR enzyme attached to another protein such as Cas13 that boosts specificity, alongside a guide RNA that targets the enzyme to the desired location (middle); or they consist of a guide RNA alone, which recruits an endogenous ADAR to edit the target sequence (right).

Infographic: RNA Editing Approaches