Progress towards the development of effective therapies for brain disorders is held back by a lack of understanding of pathological mechanisms. However, our understanding has been vastly improved by recent advances in systems biology: genomics, epigenomics, transcriptomics, proteomics, and metabolomics. Advances in metabolomics for example has demonstrated the complexity of Alzheimer’s Disease (AD) and other neurodegenerative conditions, as well as underscored the challenges in developing efficacious therapies. By defining systems-level mechanisms in neurodegenerative disease, insights into disease mechanisms can be garnered, biomarker panels can be advanced, and individualized medicine can be developed. The Scientist is bringing together a panel of experts to present their work and provide insight into the use of -omics in investigating neurological disorders.
Topics to be covered:
- Integrative proteomics for novel target and biomarker discovery in Alzheimer’s Disease
- The application of metabolomics for biomarker discovery in...
Meet the Speakers:
Nicholas Seyfried, PhD
Associate Professor, Depts. of Biochemistry & Neurology
Emory School of Medicine
Eugenia Trushina, PhD
Associate Professor, Depts. of Neurology & Pharmacology,
Director, Mitochondrial Neurobiology & Therapeutics Laboratory
Bryen A. Jordan, PhD
Associate Professor, Dominick P. Purpura Department of Neurosciences
Albert Einstein College of Medicine