Technique Talk: High-Throughput Drug Screening Using 3D Cell Culture

In this workshop, learn how to use hydrogel 3D cell culture plates for streamlined 3D cell culture colony formation, imaging, metabolic read-out, and T cell-mediated tumor cell killing.

The Scientist Creative Services Team in collaboration with MilliporeSigma
May 5, 2021

FREE Webinar

Tuesday, June 8, 2021
11:00 AM - 12:00 PM, Eastern Time

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Cells in their natural environment are surrounded by a complex extracellular matrix that provides structural and functional cues to the surrounding cells. Hydrogel plates approximate this environment in 3D cell culture but require extensive preparatory steps, including hydrogel assembly, hydrogel optimization, and cell encapsulation. 

This Technique Talk will demonstrate how to use convenient, automation-compatible, pre-cast hydrogel plates to quickly and easily establish 3D cell cultures for high-throughput screening and high content analysis.

Learning Objectives

  • Understand how TrueGel3D® HTS plates solve limitations of 3D cell culture in drug discovery
  • Learn how to set up screening assays using TrueGel3D® HTS plates
  • See how to easily establish colony formation assays
  • Know how to create 3D co-cultures of tumor spheroids and T cells using TrueGel3D® HTS plates

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Meet the Instructor:

Nina Berges, PhD
Head of Laboratory
Discovery Pharmacology
Merck Healthcare
Merck KGaA, Darmstadt, Germany

The life science business of Merck KGaA, Darmstadt, Germany operates as MilliporeSigma in the U.S. and Canada