The COVID-19 pandemic creates a need to better understand the SARS-CoV-2 immune response, including variability amongst individual human samples, temporal changes, and differences in vaccinated vs. natural immune responses. Using Simple Western automated hands-free western blotting platforms, scientists can rapidly perform SARS-CoV-2 antigen-down serology assays. The Simple Western SARS-CoV-2 Multi-Antigen Assay Module quantitatively characterizes serum or plasma human IgG antibodies reactive to five SARS-CoV-2 antigens within a 3-hour run and provides information-rich views into antibody binding profiles across individual human samples or over time. In this webinar brought to you by ProteinSimple, scientists at RAIN Incubator will present insights acquired using the Simple Western SARS-CoV-2 Multi-Antigen Assay to quickly compare human immune responses to five key viral antigens across a wide range of sample types, temporal serum draws, and dilutions.
Topics to be covered
- Data-rich profiles of human serum IgG antibodies reactive to multiple recombinant SARS-CoV-2 antigens
- Characterization of the Simple Western SARS-CoV-2 multi-antigen assay including sensitivity & comparison to an in-house SARS-CoV-2 IgG ELISA assay
- Observed variability in COVID-19 human immune responses and immune response evolution over time
- Specific immune fingerprints that may be indicative of disease progression, immunity status or other clinical outcomes
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