Gaining Biological Insights into Brain Development Using Single Cell Technologies

Richard Smith will discuss the importance of ionic flux in in utero neuronal development.

The Scientist Creative Services Team in collaboration with 10x Genomics
Apr 12, 2021

FREE Webinar

Tuesday, May 18, 2021
12:00 - 1:00 PM, Eastern Time

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Identifying key genes involved in human brain development provides novel insights into biological processes underlying the evolution of the human neocortex and the treatment of brain diseases. During prenatal brain development, ion channels are ubiquitous across several cell types, including progenitor cells and migrating neurons, but their function has been unclear. In this webinar brought to you by 10x Genomics, Richard Smith discusses how his team used single cell approaches to identify the contributions of ion-conducting proteins to human cerebral cortex development. These genetic studies and recent in utero animal modeling work suggest that precise control of ionic flux contributes to in utero developmental processes such as neural proliferation, migration, and differentiation.

Topics to be covered

  • How single cell approaches help researchers characterize human cerebral cortex development
  • The role of ionic flux in in utero developmental processes
  • The functional role for a sodium channel subtype and a sodium/potassium ATPase pump in human neocortical folding

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Meet the Speaker:

Richard Smith, PhD
Instructor
Division of Genetics and Genomics
Boston Children’s Hospital
Harvard Medical School