Improving T-cell Function in the Solid Tumor Microenvironment using Advanced Immunotherapeutic Strategies

IsoPlexis invites you to join them for an educational webinar.

Feb 22, 2019
The Scientist Creative Services Team

FREE Webinar

Thursday, April 11, 2019
2:30-4:00 PM, Eastern Time
Register Now

The solid tumor microenvironment (TME) poses many challenges for the immune system. Altered signaling pathways and metabolic constraints in combination with persistent antigen loads cause T-cell exhaustion, which in turn leads to tumor progression. Various strategies are currently in use and unde development to recover T-cell functionality in the TME. Using small-molecule blockades to enhance T-cell functionality is one avenue that researchers are exploring alongside other advanced adoptive cell therapies. To predict a patient’s response to a therapy and to optimize individual therapies, immune-cell profiling systems can be utilized for polyfunctional analysis. In this webinar brought to you by The Scientist, presented by IsoPlexis, strategies to improve T-cell function in the TME will be explored, and IsoPlexis’ Polyfunctional Strength Index (PSI) will be explained in relation to a range of TME immunotherapy challenges.

Topics to be covered:

  • Improving T-cell functionality for adoptive T-cell therapy in metastatic colon cancer, using small-molecule strategies
  • Applying polyfunction to a range of solid tumor microenvironment challenges in immunotherapy

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Meet the Speakers:

Sruthi Ravindranathan, PhD
Post Doctoral Researcher, Waller Lab
Winship Cancer Institute of Emory University


Jon Chen, MS
Director of New Collaborations
IsoPlexis