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MULTI-seq: Single-Cell Genomic Sample Multiplexing Using Lipid-Tagged Indices

In this webinar, Chris McGinnis and Jennifer Silverman discuss how MULTI-seq offers improved sample throughput and data quality.

The Scientist Creative Services Team
May 9, 2022

This webinar will be hosted live and available on-demand

Tuesday, June 14, 2022
11:00 AM Eastern Time 

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While single-cell genomic technologies can assay many thousands of unique cells per experiment, their sample throughput—the number of analyzed unique samples—remains severely limited. This hampers experimental design potential, especially for mechanistic studies, which rely on sufficient sample replicates, perturbations, and spatiotemporal information to establish causality. Sample multiplexing through technologies like MULTI-seq address this limitation by labeling cells and/or nuclear membranes with sample-specific DNA barcodes prior to single-cell isolation, allowing multiple samples to be pooled and assayed simultaneously.

In this webinar brought to you by MilliporeSigma, Chris McGinnis will describe the advantages and applications of MULTI-seq using lipid-modified oligonucleotides, including single-cell epigenomics assays, spatial transcriptomics, and single-cell chemical screens. Jennifer Silverman will discuss using the MULTI-seq Lipid-Modified Oligos kit in single-cell analysis workflows.

Topics to be covered

  • How MULTI-seq improves single-cell genomic throughput and data quality while reducing reagent costs
  • How MULTI-seq compares to other sample multiplexing technologies
  • The features and benefits of the MULTI-seq lipid-modified oligo kit

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Meet the Speakers:

Chris McGinnis, PhD
CRI Irvington Postdoctoral Fellow
Stanford University


Jennifer Silverman, PhD
Head of Molecular Assays R&D
MilliporeSigma



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