Pioneering Research in E3 Ubiquitin Ligase Biology and Applications to Drug Discovery

Jennifer Johnston discusses how a better understanding of ubiquitin-proteasome system elements can potentially aid neurodegenerative disease therapeutics.

The Scientist Creative Services Team in collaboration with Bio-Techne
Sep 15, 2021

LIVE Webinar

Wednesday, September 29, 2021
2:30 - 3:30 PM Eastern Time

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Approximately 40% of human diseases may be attributable to defects in the cellular proteostasis machinery, including the ubiquitin-proteasome system.  Accumulation of misfolded, damaged, or aggregated proteins can lead to prolonged stress, accumulation of reactive oxygen species, and cell death.  In this webinar, brought to you by Bio-Techne, Jennifer Johnston will discuss how her research of ubiquitin-proteasome system elements, including Parkin E3 ligase, is used to diagnose and treat diseases caused by defects in proteostasis pathways.

Topics to be covered

  • The basics of the ubiquitin-proteasome system
  • The biology and druggability of ubiquitin E3 ligases
  • Modifications of ubiquitin proteins and their therapeutic and diagnostic applications

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Meet the Speaker:

Jennifer Johnston, PhD
Cofounder and CEO
NysnoBio


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