Studying Cellular Heterogeneity in the Lower Urinary Tract with Spatial Transcriptomics

Anushka Dikshit, Kit Fuhrman, and Diya Joseph present how to leverage in situ hybridization and spatial genomic profiling for prostate cancer research.

The Scientist Creative Services Team in collaboration with Advanced Cell Diagnostics

LIVE Webinar

Thursday, September 23, 2021
11:00 AM - 12:30 PM, Eastern Time

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The bladder and prostate, together forming the lower urinary tract, contain a diverse collection of epithelial and stromal cell types. Spatial localization and validation of resolved cell clusters is key to making biological sense of single cell RNA-sequencing data, especially when trying to clarify the roles of novel epithelial and stromal cell types. 

In this webinar brought to you by ACD – a BioTechne brand and NanoString, Anushka Dikshit, Kit Fuhrman, and Diya Joseph will talk about integrating the capabilities of RNAscope in situ hybridization (ISH) and the GeoMx® Digital Spatial Profiler for highly sensitive spatial transcriptomics.

Topics to be covered

  • Using ISH probes for single cell detection of gene expression
  • Facilitating highly sensitive spatial transcriptomics with the GeoMx Digital Spatial Profiler
  • How these technologies can detect transcriptomic changes in atrophied glands from prostate hyperplasia patients after 5-alpha reductase inhibitor treatment

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Meet the Speakers:

Anushka Dikshit, PhD
Senior Scientist, Applications
Advanced Cell Diagnostics, a Bio-Techne brand

Kit Fuhrman, PhD
Senior Product Manager
NanoString Technologies

Diya Binoy Joseph, PhD
Postdoctoral Fellow
Department of Urology
UT Southwestern Medical Center

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