This webinar will be hosted live and available on-demand
Thursday, September 22, 2022
10:00 - 11:00 AM Eastern Time
Researchers use multiomic spatial maps to understand complex biological processes, including neovascularization and immune cell activation for cardiac remodeling after myocardial infarction. Mapping the cell-type specific molecular changes in the tissue context after myocardial infarction allows researchers to identify regional tissue repair mechanisms in the human heart and guide novel therapy development.
In this Technique Talk, Rafael Kramann will discuss spatial multiomic map development using single-cell genomics, chromatin accessibility, and spatially-resolved transcriptomics to unravel the molecular events during cardiac tissue reorganization.
- Building a spatial gene expression and gene-regulatory network map
- Investigating cellular changes after myocardial infarction
- Identifying tissue space with repair and remodeling programs
Rafael Kramann, MD, PhD, FASN
Professor of Medicine
Director, Institute of Experimental Medicine and Systems Biology
RWTH Aachen University, Germany
Director, Laboratory of Translational Kidney and Cardiovascular Research
Erasmus Medical Center, Netherlands