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Technique Talk: Understanding Cancer One Base Edit at a Time

Francisco J. Sánchez-Rivera will discuss strategies to design CRISPR base editor libraries for in vivo applications.

The Scientist Creative Services Team
May 19, 2022

This webinar will be hosted live and available on-demand

Monday,  June 20th, 2022
10:00 - 11:00 AM Eastern Time

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Single nucleotide variants (SNVs) shape cellular phenotypes and disease susceptibility in cancer. To investigate the functional consequences of SNVs, scientists use single nucleotide CRISPR base editors to make precise genetic changes.

In this Technique Talk, Francisco J. Sánchez-Rivera will discuss how to develop base editor sensor libraries for the high-throughput analysis of causative variants in preclinical cancer models.

Learning Objectives

  • How to engineer and manipulate single nucleotide bases with precision in cells and organisms
  • How single nucleotide changes influence cancer initiation and progression

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Meet the Instructor:

Francisco J. Sánchez-Rivera, PhD
Assistant Professor
Department of Biology
Koch Institute for Integrative Cancer Research
MIT

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