On their quest to improve cancer immunotherapies, scientists strive to understand how a patient’s immune function changes through interactions with tumor cells. Chronic stimulation can render T cells exhausted and limit their capacity to respond to treatment. To characterize what drives this change and to identify early indicators of T cell exhaustion, researchers perform functional proteomics on patient immune cells over the course of treatment.
In this webinar brought to you by IsoPlexis, Abhishek Garg will highlight how he performed single cell multiomics to profile T cell states in several cancer types. He will discuss how these cells behaved following immunotherapy and how this information can guide immunotherapy design for resistant cancers.
Topics to be covered
- The range of T cell states across cancer types
- Biomarkers for identifying precise clinical CD8+T cell states
- Guiding clinical application and tailoring immunotherapy to patient immune function
Meet the Speaker:
Abhishek D. Garg, PhD
Head, Laboratory of Cell Stress and Immunity
Department of Cellular and Molecular Medicine
Katholieke Universiteit Leuven ( KU Leuven )