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Our Favorite Genetics Stories of 2022
This year’s stories highlight the expanding versatility of genetic techniques and the increasing utility of such research in all life science fields.
Our Favorite Genetics Stories of 2022
Our Favorite Genetics Stories of 2022

This year’s stories highlight the expanding versatility of genetic techniques and the increasing utility of such research in all life science fields.

This year’s stories highlight the expanding versatility of genetic techniques and the increasing utility of such research in all life science fields.

RNA
2022 Top 10 Innovations 
2022 Top 10 Innovations
The Scientist Staff | Dec 12, 2022 | 10+ min read
This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.
a round water flea is illustrated in black and white on a striated background
Environmental RNA Reveals Heat Stress in Water Fleas
Katherine Irving | Dec 2, 2022 | 5 min read
The eRNA detection method could one day be used to catch early warning signs of distress in wild ecosystems. 
3D image of monkeypox virus.
Monkeypox Virus Has Potential to Be Sexually Transmitted
Jennifer Zieba, PhD | 4 min read
Researchers discovered monkeypox virus in primate testicular tissues.
Illustration from the epigenetics and the genome infographic
Infographic: How Epigenetic Marks Can Change the Genome
Katarina Zimmer | Nov 1, 2022 | 2 min read
Although epigenetic changes were long thought to largely act on the genome, rather than as part of it, research is now showing that these patterns can, directly or indirectly, change the genetic code.
Cellular DNA and epigenetics
Do Epigenetic Changes Influence Evolution?
Katarina Zimmer | Nov 1, 2022 | 10+ min read
Evidence is mounting that epigenetic marks on DNA can influence future generations in a variety of ways. But how such phenomena might affect large-scale evolutionary processes is hotly debated.
Technique Talk: Single-Cell Spatial Transcriptomics with Cleavable Fluorescent Probes 
Single-Cell Spatial Transcriptomics with Cleavable Fluorescent Probes 
The Scientist Creative Services Team | 1 min read
In this webinar, Jia Guo discusses the basics of in situ hybridization and how to use novel fluorescent probes for ultra-sensitive single-cell resolution in situ genomics.
Photo of Ankara Jain in his lab
Ankur Jain Explores RNA Aggregations in Neurodegenerative Disease
Hannah Thomasy | Oct 3, 2022 | 3 min read
The MIT biologist studies how RNA molecules self-assemble and the role these accumulations may play in diseases such as ALS and Huntington’s.
Conceptual image showing molecules making up a brain shape
The Noncoding Regulators of the Brain
Christie Wilcox, PhD | Sep 12, 2022 | 10+ min read
Noncoding RNAs are proving to be critical players in the evolution of brain anatomy and cognitive complexity.
Fluorescent microscopy images of cells after being transfected.
Universal Transfection Reagents: Improving Efficiency and Decreasing Cell Toxicity
The Scientist Creative Services Team, MilliporeSigma, and Roche | 4 min read
Researchers optimize their transfection protocols with the ideal transfection reagent that has multiple applications, low cytotoxicity, and high transfection efficiency.
Illustration of RNAs
Infographic: Noncoding RNA in the Brain
Christie Wilcox, PhD | Sep 12, 2022 | 4 min read
Neurologically important noncoding RNAs come in many shapes and sizes.
A photograph of Christine Guthrie and Hiten Madhani
RNA Pioneer Christine Guthrie Dies at 77
Amanda Heidt | Sep 1, 2022 | 5 min read
Guthrie established foundational concepts in the field of pre-mRNA splicing during her career at the University of California, San Francisco.
Discover How to Design Sensitive Nucleic Acid Lateral Flow Assays
Go with the Flow: Adapting Lateral Flow Assays for Nucleic Acid Detection
The Scientist Creative Services Team and nanoComposix | 1 min read
Scientists incorporate sensitive nanoparticles to rapidly detect DNA and RNA.
Histological slide showing cancerous prostate tissue
2D Genetic Map of Prostate Cells Charts Cancer Growth
Holly Barker | Aug 23, 2022 | 4 min read
An in situ map of copy number variations in prostate tissue reveals that purportedly cancerous genomic changes frequently occur in the healthy tissue surrounding tumors.
A twisted and folded illustration of single-stranded RNA in front of a blue background.
Deficient RNA Editing Implicated in Inflammatory Disease 
Alejandra Manjarrez, PhD | Aug 5, 2022 | 3 min read
Genetic variants that reduce the editing levels of double-stranded RNA are associated with autoimmune and immune-mediated conditions, a study finds.
Learn How Cutting-Edge Science is Breaking Through Industry Barriers
Focus on Innovation: Scientific Advances Driving Biopharma Market Trends
The Scientist Creative Services Team and Tecan | 1 min read
Explore the future of biopharma research and development.
Ribonucleic acid strands consisting of nucleotides important for protein bio-synthesis
Katharina Höfer Probes the Machinery of Bacterial Gene Expression
Hannah Thomasy | Jun 13, 2022 | 3 min read
The molecular biologist studies how chemical modifications to RNA building blocks change the way RNA regulates complex cellular processes.
Illustration of pink strands of RNA on a blue background
Synthetic RNA Can Build Peptides, Hinting at Life’s Beginnings
Jef Akst | May 12, 2022 | 2 min read
Researchers engineered strands of RNA that can link amino acids together, suggesting a way that RNA and proteins may have emerged together to create the earliest forms of life.
Discover how to Select and Design qPCR Probes
Selecting Probes That Rise to Any qPCR Challenge
The Scientist Creative Services Team and LGC Biosearch Technologies | 1 min read
Learn how to select qPCR probes that match downstream applications.
Illustration of a meteorite shower heading for Earth
All RNA and DNA Base Types Are Found in Meteorites, Study Claims
Catherine Offord | Apr 27, 2022 | 2 min read
The discovery could add weight to the hypothesis that the building blocks of life on Earth originally came from space, but some scientists note the possibility of contamination.
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