adipose tissue
Breaking the Cancer-Obesity Link
Breaking the Cancer-Obesity Link
Laura W. Bowers, Stephen D. Hursting, Ciara H. O’Flanagan | Nov 1, 2015
Obese people are at higher risk for developing cancer, have worse prognoses once diagnosed, and are often resistant to chemotherapy regimens. The question is, Why?
A Complex Disorder
A Complex Disorder
Stephen D. Hursting, Ciara H. O’Flanagan, Laura W. Bowers | Nov 1, 2015
Factors that likely contribute to obesity include disruptions to intercellular signaling, increased inflammation, and changes to the gut microbiome.
 
Warming Up to Brown Fat
Warming Up to Brown Fat
Kerry Grens | Oct 8, 2015
Scientists know how to turn on these fat-combusting cells. Can these energy burners be used to combat obesity?
Neuronal Connection Between Fat and the Brain Visualized
Neuronal Connection Between Fat and the Brain Visualized
Anna Azvolinsky | Sep 24, 2015
Researchers pinpoint the neurons within white fat tissue that mediate brain-bound leptin signaling and eventual fat breakdown.
Burn Victims Produce Brown Fat
Burn Victims Produce Brown Fat
Kerry Grens | Aug 7, 2015
Following extreme trauma, patients’ adipose samples have revealed—for the first time in humans—that white fat can be converted into energy-burning brown fat.
Bone Marrow Makes New Fat Cells
Bone Marrow Makes New Fat Cells
Ashley P. Taylor | Jul 16, 2015
The origins of adipocytes have been hotly debated, but a human study supports the idea that the bone marrow takes part. 
Brain’s Role in Browning White Fat
Brain’s Role in Browning White Fat
Anna Azvolinsky | Jan 15, 2015
Insulin and leptin act on specialized neurons in the mouse hypothalamus to promote conversion of white to beige fat.
Week in Review: October 6–10
Week in Review: October 6–10
Jef Akst | Oct 10, 2014
Nobel Prizes awarded; transgenerational effects of mitochondrial mutations; fat-targeted gene knockdown; Ebola updates in Spain and U.S.
Next Generation: Fat-Targeted Gene Knockdown
Next Generation: Fat-Targeted Gene Knockdown
Molly Sharlach | Oct 5, 2014
A small peptide helps a silencing construct home in on the adipocytes of obese mice.
Markers Distinguish “Good” from “Bad” Fat
Markers Distinguish “Good” from “Bad” Fat
Anna Azvolinsky | Jul 30, 2014
Researchers have identified three fat cell-specific surface markers that distinguish white from brown and beige adipocytes.