ISTOCK, OONAL
Questions Raised About “Breakthrough” Therapies’ Clinical Support
Questions Raised About “Breakthrough” Therapies’ Clinical Support
Compared to other drugs, therapeutics given breakthrough status receive FDA approval on the basis of weaker trial evidence, a study finds.
Questions Raised About “Breakthrough” Therapies’ Clinical Support
Questions Raised About “Breakthrough” Therapies’ Clinical Support

Compared to other drugs, therapeutics given breakthrough status receive FDA approval on the basis of weaker trial evidence, a study finds.

Compared to other drugs, therapeutics given breakthrough status receive FDA approval on the basis of weaker trial evidence, a study finds.

approvals, developmental biology, neuroscience, evolution
Synthetic Botox Treats Chronic Pain in Mice
Synthetic Botox Treats Chronic Pain in Mice
Abby Olena | Jul 18, 2018
Researchers silence pain neurons in the mouse spinal cord with injections of botulinum toxins modified to bind to the neurons’ receptors.
Image of the Day: Not All Bad
Image of the Day: Not All Bad
Sukanya Charuchandra | Jul 16, 2018
In zebrafish, some amount of reactive oxygen species is required for normal development.
A Noninvasive Way to Control Individual Brain Regions
A Noninvasive Way to Control Individual Brain Regions
Catherine Offord | Jul 13, 2018
Researchers use a combination of ultrasound waves, genetic engineering, and synthetic drugs to switch specific neurons on and off in mice.
Higher Blood Pressure Has Links to Brain Lesions in Older Adults
Higher Blood Pressure Has Links to Brain Lesions in Older Adults
Sukanya Charuchandra | Jul 13, 2018
In a longitudinal study, researchers find that elderly people with higher pressure were more likely to show signs of Alzheimer’s disease in brain tissue.
Exosomes in Blood Indicate Mild TBI: Study
Exosomes in Blood Indicate Mild TBI: Study
Ashley Yeager | Jul 13, 2018
Levels of tau, amyloid-β 42, and IL-10 extracted from extracellular vesicles that started out in the brain were higher in military personal suffering head injuries compared with healthy soldiers.
Horizontal Gene Transfer in Bdelloid Rotifers Questioned
Horizontal Gene Transfer in Bdelloid Rotifers Questioned
Abby Olena | Jul 12, 2018
A re-analysis of sequencing data from a 2016 study of these tiny metazoans reveals possible contamination, rather than an exchange of DNA among species.
Hominins Left Africa for Asia Much Earlier Than Thought
Hominins Left Africa for Asia Much Earlier Than Thought
Shawna Williams | Jul 11, 2018
The dating of stone tools in China puts members of the Homo genus there more than 2 million years ago.
Original North American Dogs Descended From Siberian Populations
Original North American Dogs Descended From Siberian Populations
Catherine Offord | Jul 5, 2018
European settlers likely wiped out these ancient dogs, but the animals seem to have left a lasting legacy in a transmissible canine cancer.
Forgotten Memories Brought Back in Mice
Forgotten Memories Brought Back in Mice
Sukanya Charuchandra | Jul 5, 2018
By stimulating specific neurons in mouse brains, researchers demonstrate that memories from infancy are not lost, but merely difficult to access.