biobusiness, drug development, biotech
Opinion: Label Drugs That Are Tested on Animals
Opinion: Label Drugs That Are Tested on Animals
Shaun Khoo | Jan 16, 2018
Transparency about the role of animals in drug development could help raise awareness of and appreciation for preclinical research.
Child Receives Transgenic Skin
Child Receives Transgenic Skin
Ruth Williams | Jan 1, 2018
A combination gene-and-cell therapy has given a boy with a grievous skin disease a new lease on life, and resolved a dermatology debate to boot.
Sex Differences in Opioid Analgesia: A Complicated Picture
Sex Differences in Opioid Analgesia: A Complicated Picture
Catherine Offord | Jan 1, 2018
Researchers are beginning to tease apart the mechanisms underlying differences in how males and females respond to powerful painkillers.
Targeting Sodium Channels for Pain Relief
Targeting Sodium Channels for Pain Relief
Catherine Offord | Jan 1, 2018
The race to develop analgesic drugs that inhibit sodium channel NaV1.7 is revealing a complex sensory role for the protein.
Animal Analgesics
Animal Analgesics
The Scientist Staff | Jan 1, 2018
A cornucopia of toxins in the animal kingdom could provide inspiration for novel painkillers, but so far, effective drugs have proven elusive.
 
Novel Analgesics at a Snail’s Pace
Novel Analgesics at a Snail’s Pace
Bob Grant | Jan 1, 2018
Studying cone snail venom has yielded novel pain pathways, but the peptides that function as toxins are difficult to translate into drugs.
Researchers Mine Centipede Toxins for Analgesics
Researchers Mine Centipede Toxins for Analgesics
Catherine Offord | Jan 1, 2018
Venomous centipedes may harbor a clue to the creation of a successful pain-killing compound for humans.
Mining Spider Toxins for Analgesic Clues
Mining Spider Toxins for Analgesic Clues
Catherine Offord | Jan 1, 2018
Arachnids harbor a plentiful array of molecules that target mammalian pain receptors.
Toxin from a Dangerous Fish Delicacy
Toxin from a Dangerous Fish Delicacy
Kerry Grens | Jan 1, 2018
In tiny doses, the pufferfish’s tetrodotoxin can be turned into a pain-relieving ion channel blocker.
Sourcing Painkillers from Scorpions’ Stings
Sourcing Painkillers from Scorpions’ Stings
Abby Olena | Jan 1, 2018
Compounds in the arachnids’ venom interact with ion channels to both cause and block pain.