BRCA1, culture, immunology
Book Excerpt from <em>The Power of Rare</em>
Book Excerpt from The Power of Rare
Victoria Jackson, Michael Yeaman | May 1, 2018
In chapter 4, “Building a Cure Machine,” author Victoria Jackson reveals the challenges in launching a foundation focused on funding research on a rare disease.
Preterm Labor May Be Sparked by Fetal Immune Reaction
Preterm Labor May Be Sparked by Fetal Immune Reaction
Ruth Williams | Apr 25, 2018
Immune cells targeting maternal antigens are abundant in the blood of premature infants, suggesting fetal intolerance of mom may instigate early labor.  
Image of the Day: Immune Cell In Action
Image of the Day: Immune Cell In Action
The Scientist Staff | Apr 23, 2018
By combining two new microscopy technologies, researchers filmed immune cells toiling away in the inner ear of a living zebrafish.
Antibody Combo Expands Response to Checkpoint Inhibitor in Mice
Antibody Combo Expands Response to Checkpoint Inhibitor in Mice
Kerry Grens | Apr 16, 2018
Genetic analyses uncover cellular hallmarks of bladder cancer tumors that don’t respond, but interfering with one of those characteristics in a mouse model causes tumors to shrink.  
New Ovarian Cancer Vaccine Shows Promise
New Ovarian Cancer Vaccine Shows Promise
Catherine Offord | Apr 12, 2018
A preliminary clinical trial finds that the personalized therapy improves survival rates and has no severe side-effects.
Some Antibiotics Rev Up Host Immune Response to Viruses
Some Antibiotics Rev Up Host Immune Response to Viruses
Shawna Williams | Apr 9, 2018
The antimicrobial drug neomycin protects mice from some viral infections, complicating the picture of the relationship between antibiotics and susceptibility to viruses.
Opinion: We Have Been Naive About Naive T Cells
Opinion: We Have Been Naive About Naive T Cells
José A.M. Borghans, Femke van Wijk, Theo van den Broek | Apr 6, 2018
Human naive T cells are far more heterogeneous than has long been appreciated, having implications for vaccine strategies.
Ruth Nussenzweig, Malaria Researcher, Dies
Ruth Nussenzweig, Malaria Researcher, Dies
Jim Daley | Apr 5, 2018
The microbiologist’s research led to the development of the first human malaria vaccine.
A Neuroscientist’s Journey Through Madness
A Neuroscientist’s Journey Through Madness
Barbara Lipska with Elaine McArdle | Apr 1, 2018
After I was diagnosed with brain cancer and started to lose my mental health, the importance of my job came into clear focus.
PARP Inhibitors Are Improving the Outlook of Hard-to-Treat Cancers
PARP Inhibitors Are Improving the Outlook of Hard-to-Treat Cancers
Vicki Brower | Apr 1, 2018
With three recent FDA approvals, and a number of Phase 3 trials ongoing, the drugs are seeing a surge in interest.