Cancer cell
Interrogating the Complexities of the Tumor Microenvironment
Alison Halliday, PhD | May 19, 2023 | 5 min read
Gaining a better understanding of the dynamic and reciprocal interactions between cancer cells and the tumor microenvironment is essential for improving patient diagnosis and treatment.
Semi-circle of colorful cancer awareness ribbons
Electric Fields Disrupt Cancer Cell Division
Danielle Gerhard, PhD | May 4, 2023 | 5 min read
A novel, non-invasive treatment using electrical currents exploits physiological properties of dividing cancer cells to prolong survival and augment current therapies.
Test tubes containing liquid biopsy samples with circulating tumor DNA (ctDNA)
Supporting the Evolution of Liquid Biopsies
The Scientist Creative Services Team in collaboration with Twist Bioscience | 1 min read
Sequencing circulating tumor DNA (ctDNA) within liquid biopsies permits tumor identification and tracking. 
Composition of DNA with a glitch effect
“Silent” Mutations Make Noise In Cancer
Katarina Zimmer | May 1, 2023 | 10+ min read
Synonymous mutations have long been ignored in cancer studies since they don’t affect the amino acid sequences of proteins. But research increasingly reveals that they can have disease-driving effects.
Transcription illustration
Infographic: How “Silent” Mutations Can Disrupt Protein-Making
Katarina Zimmer | May 1, 2023 | 3 min read
Although scientists often assume that synonymous mutations don’t cause any biological effects because they don’t alter the amino acid code, recent research shows that they can influence transcription and translation in a variety of ways. 
Benign or Cancerous? Differentiating Mutation Types with Machine Learning
Benign or Cancerous? Differentiating Mutation Types with Machine Learning
The Scientist’s Creative Services Team | 2 min read
Scientists turn to machine learning and big data approaches for precision -omics in cancer research.
Engineered T cells attacking a cancer cell
Helping Engineered T Cells Find Their Way to Tumors
Nele Haelterman, PhD | Apr 18, 2023 | 3 min read
Susan Thomas discusses how her team engineered a microfluidic device to screen for T cells with improved homing capability to tumor cells. 
Green and brown illustration of cancer cells in front of a peach and yellow background.
Bacterial Tractor Beams Bring Radiation to Tumors
Rachael Moeller Gorman | Apr 17, 2023 | 3 min read
Colonizing tumors with engineered bacteria may allow researchers to target sites currently inaccessible to radionuclide therapy.
3D rendered image of multiple antibody-drug conjugate next generation antibodies.
Advances in Antibody Therapeutics
Elina Kadriu | 4 min read
Scientists engineer therapeutic antibodies with improved stability and efficacy. 
Histological stain of in blue, red, and green of tumor
Self-Charging Battery Battles Tumors in Mice
Natalia Mesa, PhD | Apr 4, 2023 | 3 min read
A battery that charges itself in salty fluids starves tumors of oxygen, helping improve some drugs treat cancer, a study finds.
electron micrograph of grey cancer cell, with two red T cells stuck to the side
Translation of “Jumping Genes” Creates Cancer Therapy Targets
Natalia Mesa, PhD | Mar 29, 2023 | 4 min read
Researchers find many tumor-specific antigens form when cancer genes and transposable elements link up.
Learn how cell-free DNA is used for disease biomarker detection
Cell-Free DNA in Clinical Diagnostics
Tecan | 1 min read
Advancements in measuring DNA in bodily fluids create new opportunities for understanding disease.
Two malignant cancer cells protruding towards each other.
The Role of Adhesion Receptors in Cancer Cannibalism
Elina Kadriu | Mar 13, 2023 | 3 min read
Contact inhibition of locomotion by adhesion receptors prevents cancer cells from eating each other. 
Michael Green smiling at the camera in front of a shelf in the lab
Molecular Biologist Michael Green Dies at 69
Lisa Winter | Mar 7, 2023 | 2 min read
Beyond his achievements in academia, he also cofounded three pharmaceutical companies and filed 15 patents related to cancer therapeutics. 
A Spotlight on Cancer Cell Metabolism
A Spotlight on Cancer Cell Metabolism
The Scientist’s Creative Services Team | 1 min read
In this webinar, Elena Piskounova and Christina Towers discuss the implications of metabolic changes in cancer cells for therapeutic development and efficacy. 
Microscopy image of blue stained cohesin proteins.
Mutated Cohesin Throws DNA Splicing out of Whack, Resulting in Cancer
Shafaq Zia | Mar 3, 2023 | 2 min read
Cohesin mutations cause dysregulations in alternative splicing, contributing to tumor initiation and progression, a study finds. 
Histological image of ccRCC
Mutational Signature Indicates Risk of Kidney Cancer Recurrence
Holly Barker, PhD | Mar 1, 2023 | 2 min read
DNA sequencing can identify mutations that predict recurrence of renal cell carcinoma and may help low-risk patients avoid unnecessary treatment, a study finds.
Understanding How Single Cell Evolution Drives Tumor Complexity
Understanding How Single Cell Evolution Drives Tumor Complexity
The Scientist’s Creative Services Team | 1 min read
Andris Abramenkovs and Mark Lynch will discuss how to overcome challenges obtaining high-definition genomic data from single cells.
Infographic showing transposable elements in cancer
Infographic: Transposable elements in cancer
Diana Kwon | Mar 1, 2023 | 1 min read
Jumping genes are let loose in cancerous cells, with multiple effects on cell health.
Artists' renditions of cancer cells and tRNA molecules superimposed over one another.
Long noncoding RNAs and Microproteins Can Spark Cancer—or Sometimes Squelch It
Rachael Moeller Gorman | Mar 1, 2023 | 10+ min read
Noncoding RNAs and microproteins, once considered genomic noise, are turning out to be critical to the progression of some types of cancer.