fingertips with pills on them
Over the Counter Antihistamines Could Help Against Cancer
Alejandra Manjarrez | Nov 24, 2021
The binding of histamine with one of its receptors within the tumor environment makes cancer cells more resistant to immunotherapy, according to a new study. Blocking that binding could improve responses to treatment.
grey and purple cancer cells under a microscope
Cell Diversity Could Spell Trouble for Animal Models of Cancer
David Adam | Nov 19, 2021
Tracking human cancers in mice shows some unexpected cell changes that could undermine translational research.  
Image of the tissue surrounding a pancreatic tumor thickening and scarring.
How Pancreas Injuries Can Cause Cancer in Mice
Dan Robitzski | Nov 9, 2021
A key mutation turns healing cells into cancer promoters.
man standing in front of gene sequencing machines
Q&A: Nearly Every Single Human Gene Can Be Linked to Cancer
Dan Robitzski | Oct 29, 2021
The Scientist spoke with University of Liverpool aging and longevity researcher João Pedro de Magalhães about how human biases can influence scientific priorities and outcomes in genetics.
An artist's rendition of an RNA molecule in light blue on a dark blue background
Same RNA Acts in Neurodegeneration and Cancer
Abby Olena | Oct 29, 2021
The long noncoding RNA MINCR, implicated in ALS and Alzheimer’s disease as well as several types of cancer, appears to function differently when present at high versus low levels.
brain scan showing uptake of tratuzumab into tumor (arrow)
Sound Waves Aid Brain Tumor Treatment
Ruth Williams | Oct 13, 2021
In a small clinical study, focusing ultrasound beams on tumors in patients’ brains helped open the blood-brain barrier to facilitate drug delivery.
blind mole rat
Blind Mole Rats Use Junk DNA to Combat Cancer
Ruth Williams | Sep 30, 2021
Activation of retrotransposons in the animals’ cancerous cells sets off an innate immune response that triggers cell death.
salt on a black background
Salty Diet Helps Gut Bugs Fight Cancer in Mice: Study
Sophie Fessl | Sep 20, 2021
A high-salt diet suppressed the growth of tumors in a mouse model of melanoma, apparently because of an interplay between the gut microbiome and natural killer cells.
A multicolored section of a fruit fly brain
Tumors Disrupt the Blood-Brain Barrier at a Distance
Abby Olena | Sep 9, 2021
Shoring up the tissues that separate neurons and other brain cells from the circulatory system in fruit flies and mice can prolong life in the presence of a tumor.
Two emergency responders stand near a barricade on a street in New York
Q&A: Health of 9/11 First Responders 20 Years Later
Amanda Heidt | Sep 7, 2021
The Scientist spoke with Rachel Zeig-Owens, the director of epidemiology for the World Trade Center Health Program, about what scientists have learned after two decades of studying illness and disease among survivors.
A medical linear accelerator used to deliver radiation therapy
Tool Would Use Tumor Gene Expression to Inform Radiation Dose
Alejandra Manjarrez | Aug 27, 2021
In a retrospective analysis, a team found that an algorithm integrating the gene expression of a tumor with the radiation dose a patient received predicted how well the patient responded to the treatment.
white and yellow colonies growing on a petri dish
Gut Fungi Hamper Radiation Therapy in Mice with Cancer
Rachael Moeller Gorman | Aug 11, 2021
Depleting intestinal fungi allows radiation to effectively fight cancer, likely because the microbes influence the antitumor immune response.
visualization of p53 protein interacting with its inhibitors MDM2 and MDMX
p53 Unleashes Endogenous Retroviruses to Tackle Tumors: Study
Marcus A. Banks | Jul 29, 2021
New experiments suggest the famous tumor-suppressing protein uses viral elements lingering in the genome to get cancerous cells to announce their presence to the immune system.
streaks of blue and green from a fluorescent chromosome mapping technique
Optical Genome Mapping Works Well in Detecting Cancer Risk
Marcus A. Banks | Jul 22, 2021
The relatively new technique for visually detecting chromosomal variants associated with disease risk performs at least as well as more established techniques in two recent studies.