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Collection of pink, green, blue, yellow, and green cubes with A, G, T, C, and a double helix printed on them.
An Overlooked Nucleotide Recycling Pathway Fuels Tumor Growth
Alejandra Manjarrez, PhD | Sep 23, 2024 | 4 min read
When it comes to supplying their purine needs, cancer cells may use salvaged metabolites, according to a study in mice. 
An illustration of a single cancer cell (in seafoam green) with four white blood cells (in green) attached to it.
The Circadian Clock Tells the Right Time for Immunotherapy
Sahana Sitaraman, PhD | Sep 23, 2024 | 4 min read
Administering immunotherapy when the tumor microenvironment is most susceptible to T cells enhances treatment efficacy in mice.
Improving T Cell Tumor-Specificity Using Single Cell Co-culture
Improving T Cell Tumor-Specificity Using Single Cell Co-culture
The Scientist Staff | 1 min read
In this webinar, Edward Han, Jospeh Zenga, and Tyce Kearl will discuss how optofluidic technologies unlock key immuno-oncology insights for translational applications.
A dark blue T cell with light blue and yellow structures on its surface.
Epigenetic Clocks Continue to Tick Over Multiple Lifetimes
Hannah Thomasy, PhD | Sep 17, 2024 | 5 min read
Murine T cells that survived at least four host lifetimes offer insights into immunological senescence. 
Conceptual image of hands wearing surgical gloves holding a test tube filled with a liquid biopsy sample.
Enhanced Sequencing Results from Liquid Biopsies
The Scientist Staff | Sep 16, 2024 | 2 min read
Using a library preparation kit optimized for cell free DNA (cfDNA) provides high quality data for early cancer detection.
An illustration of pink cancer cells attached to a blue surface.
Delving Deeper: Advancing Cancer Research with Molecular Analysis
The Scientist Creative Services Team in collaboration with Thermo Fisher Scientific | 1 min read
The emergence of innovative analytical methods empowers researchers to comprehensively characterize tumor samples.
Image of a cancer cell skipping across the water. 
Skipping Toward Resistance: The Gradual Adaptation of Cancer Cells 
Laura Tran, PhD | Sep 6, 2024 | 4 min read
Instead of an on-off toggle switch, cancer cells adapt through a series of distinct states of increasing drug resistance.
This image shows hexagon shaped cells (mouse airway stem cells) that are outlined in magenta. Within each cell there are tiny dots that represent centrioles, which are colored cyan. 
Introducing a New Version of the Cell Cycle
Maggie Chen | Sep 6, 2024 | 4 min read
Scientists have identified a new variant of the cell cycle that could provide insight into how diseases like cancer occur. 
A blue T cell attacks a blue cancer cell
Characterizing Cancer via the Immune Response
The Scientist | 1 min read
Researchers explore the immune system to further understand cancer and illuminate therapy development.
A 3D render of multiple RNA strands floating around each other.
Improving RNA Sequencing with FFPE Samples
The Scientist Staff | Sep 2, 2024 | 2 min read
Samples are commonly stored in a way that degrades RNA. Scientists are devising new ways to overcome this obstacle for RNA sequencing. 
Pseudo-colored scanning electron microscope image of the algae microrobot with the algae in green and the drug-filled nanoparticles in orange.
Green Warriors: Algae Microrobots Set to Combat Metastasis
Laura Tran, PhD | Aug 26, 2024 | 4 min read
Green algae can be outfitted with nanoparticles, transforming them into efficient drug-delivering machines that target lung tumors.
Exploring the Tumor Microenvironment with Spatial Biology
Exploring the Tumor Microenvironment with Spatial Biology
The Scientist Staff | 1 min read
In this webinar, Pinaki Bose and Fei Chen will discuss how scientists use spatial biology techniques to study the tumor microenvironment.
Cartoon image of floating transparent spheres with smaller blue spheres inside them.
Study Reveals a Cell-Eat-Cell World
Aparna Nathan, PhD | Aug 13, 2024 | 3 min read
From normal vertebrate development to tumor cell cannibalism, cell-in-cell events occur in many different contexts across the tree of life
Artistic rendering of a tumor cell as a misshapen purple blob, surrounded by spiky pink blobs representing NK cells.
Maintaining NK Cells’ Killer Instincts
Aparna Nathan, PhD | Aug 9, 2024 | 4 min read
A protein in natural killer cells keeps them from turning into more docile counterparts.
T-cell targeting cancer cells
Cell-Based Assays for Immuno-Oncology
Lonza | 1 min read
Cellular immunogenicity and immunotoxicity assays help scientists design, validate, and translate therapeutic research into treatments that weaponize the immune response against cancer.
An illustration of circulating tumor cells surrounded by red blood cells.
Monitoring Multiple Myeloma Progression through Sequencing
Charlene Lancaster, PhD | Aug 2, 2024 | 4 min read
Irene Ghobrial sequences circulating tumor cells in blood samples to genomically profile patients with multiple myeloma.
A 3D rendering of an antibody drug conjugate with attached cytotoxic payloads.
Supporting Antibody-Drug Conjugate Development
The Scientist Staff | Aug 1, 2024 | 2 min read
Industry expertise helps scientists navigate and streamline antibody-drug conjugate research and development.
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Understanding the Effects of Extrachromosomal DNA on Cancer
The Scientist | 1 min read
Lukas Chavez uses multiomic techniques to study how extrachromosomal DNA (ecDNA) contributes to tumor heterogeneity and gene expression changes in medulloblastoma.
A melanoma on human skin.
Minicells Shut Down Cancer’s Spread 
RJ Mackenzie | Jul 29, 2024 | 4 min read
A nutrient-based nanomedicine stopped runaway tumor growth in mice by firing up a latent metabolic pathway.
A fluorescent imaginal disc from <em >Drosophila&nbsp;</em>larvae on a black background.
Cancers with an Exceptional Cause
Kamal Nahas, PhD | Jul 18, 2024 | 4 min read
Epigenetic control of gene expression can switch on genes that push cell division into overdrive independently of genetic faults.
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