Mice Inherit Cancer Susceptibility Via Epigenetic Changes in Sperm
Mice Inherit Cancer Susceptibility Via Epigenetic Changes in Sperm
Mouse fathers whose sperm lacks the gene Kdm6a pass down altered methylation patterns to male offspring, along with a better chance of developing tumors and dying.
Mice Inherit Cancer Susceptibility Via Epigenetic Changes in Sperm
Mice Inherit Cancer Susceptibility Via Epigenetic Changes in Sperm

Mouse fathers whose sperm lacks the gene Kdm6a pass down altered methylation patterns to male offspring, along with a better chance of developing tumors and dying.

Mouse fathers whose sperm lacks the gene Kdm6a pass down altered methylation patterns to male offspring, along with a better chance of developing tumors and dying.

cancer
Two Patients Treated with CRISPRed Cells in Immunotherapy Trial
Two Patients Treated with CRISPRed Cells in Immunotherapy Trial
Shawna Williams | Apr 16, 2019
One person with multiple myeloma and one with sarcoma are the first so far to receive the genetically engineered T cells in the study.
Q&A: Epigenetic Therapies for Breast Cancer
Q&A: Epigenetic Therapies for Breast Cancer
Katarina Zimmer | Apr 4, 2019
Breast cancer researcher and oncologist Nancy Davidson discusses what we’ve learned from the first wave of epigenetic trials for breast cancer, and what challenges lie ahead before such therapies reach the clinic.
Exosomes from Blood Carry RNA Signatures of Liver Cancer
Exosomes from Blood Carry RNA Signatures of Liver Cancer
Emma Yasinski | Apr 2, 2019
A small study finds that the tiny extracellular vesicles from patients with hepatocellular carcinoma have RNA content distinct from patients with cirrhosis only.
Q&A: A 10,000-Genome Milestone for Shared Pediatric Cancer Data  
Q&A: A 10,000-Genome Milestone for Shared Pediatric Cancer Data  
Carolyn Wilke | Apr 1, 2019
Computational biologist Jinghui Zhang of St. Jude realized scientists could work more efficiently with tools and genomic data shared on the cloud.
Mopping Up Excess Chemotherapy Drugs
Mopping Up Excess Chemotherapy Drugs
Ruth Williams | Apr 1, 2019
A prototype in-vein device would collect toxic medications before they reach healthy tissues.
Scientists Take Aim at Disease-Causing RNAs Using Small-Molecule Drugs
Scientists Take Aim at Disease-Causing RNAs Using Small-Molecule Drugs
Claire Asher | Apr 1, 2019
Renewed interest from the biotech industry sparks hope for drugging the nucleic acid to treat cancer and other conditions.
Tuberculosis Can Emerge After Cancer Immunotherapy
Tuberculosis Can Emerge After Cancer Immunotherapy
Ashley Yeager | Apr 1, 2019
At least a handful of patients have developed active TB after receiving cancer treatment designed to boost the immune system’s antitumor response.
Ten-Minute Sabbatical
Ten-Minute Sabbatical
The Scientist Staff | Apr 1, 2019
Take a break from the bench to puzzle and peruse.
A Review of <em>Everything in Its Place: First Loves and Last Tales</em>
A Review of Everything in Its Place: First Loves and Last Tales
Bob Grant | Apr 1, 2019
This posthumously published collection of essays by Oliver Sacks further cements the neurologist’s place in the pantheon of science writers.