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Images of tumor organoids acquired using high-speed live cell interferometry.
Evaluating Tumor Heterogeneity with a High Throughput Pipeline
Charlene Lancaster, PhD | Jun 3, 2024 | 3 min read
An automated bioprinting and imaging platform allows researchers to examine heterogeneous responses to anticancer drugs within a tumor organoid population.
An illustration showing the DNA inside an immune cell. Other immune cells are shown in the background. 
Keeping CAR T Cells Sharp 
Aparna Nathan, PhD | May 21, 2024 | 4 min read
The FOXO1 transcription factor boosts T cells’ memory and reduces dysfunction.
An illustration of cells growing in the presence of cytokines.
Advancing Immunotherapy Development with High-Quality Cytokines
The Scientist and Sino Biological | 3 min read
Superior quality cytokines are crucial for reliable research results and the safe production of cancer cell therapies.
An artistic illustration of the female reproductive system.
Outsmarting Ovarian Cancer
Mariella Bodemeier Loayza Careaga, PhD | May 8, 2024 | 4 min read
Biochemist Sharon Stack hopes to advance the field of ovarian cancer by exploring the tumor and host-related factors that influence its metastatic process. 
Two cells fluorescently stained for normal (red) and damaged (green) lysosomes.
Cancer Cells Spread When They Stop Recycling Waste
Kamal Nahas, PhD | May 8, 2024 | 4 min read
An immune-inhibiting protein that regulates autophagy halts breast cancers from venturing across tissue borders.
Optimers Bring Precision to Cancer Research and Therapeutics
Optimers Bring Precision to Cancer Research and Therapeutics
The Scientist Staff | 1 min read
In this webinar, David Bunka will discuss how scientists can use Optimer® binders in cancer research. 
Cuboidal DNA origami block containing parallel double helices (gray columns) decorated with tumor antigens (green proteins) and CpG adjuvants (yellow helices) on opposing faces.
Fighting Tumors with DNA Origami
Kamal Nahas, PhD | May 6, 2024 | 5 min read
Researchers bolster antitumor immune defenses using cancer vaccines made from DNA origami.
Close-up painting of hands drawing the DNA helix.
Measuring Mutagenesis with Precision Genome Editing
Deanna MacNeil, PhD | May 3, 2024 | 5 min read
A new prime editing sensor library targeting p53 mutations allowed scientists to interrogate thousands of tumor genotypes as they arose in endogenous contexts.
Viewing the Glioblastoma Tumor Microenvironment at Single Cell Resolution
Viewing the Glioblastoma Tumor Microenvironment at Single Cell Resolution
The Scientist Staff | 1 min read
In this webinar, Matthias Brendel will discuss a new PET approach called scRadiotracing, which involves immunomagnetic cell sorting after in vivo radiotracer injection combined with 3D histology.
3D rendered DNA strand and cancer cell 
Translating ctDNA Detection into Breast Cancer Research Breakthroughs
The Scientist Staff | May 1, 2024 | 2 min read
Noninvasive methods to monitor traces of cancer left over after treatment may lead to better early interventions.
A microscopy image stained for different cell populations in breast tumors.
Cancer Cells Give Orders
Holly Barker, PhD | Apr 23, 2024 | 4 min read
Cancer-supporting cells control their neighbors’ behavior using an often-overlooked protein delivery system. 
New Research Avenues Provide Hope for Metastatic Disease
New Research Avenues Provide Hope for Metastatic Disease
The Scientist Staff | 2 min read
Learn about the latest cellular studies that help researchers discover the mechanisms of cancer metastasis.
A scanned image of stained mouse pulmonary tissue.
Lung Cancer Cells Switch Oncogenic Drivers
Alejandra Manjarrez, PhD | Apr 23, 2024 | 3 min read
Mouse models mimicking the transition from a common form of lung cancer to a more aggressive one may help scientists develop future strategies to prevent this transformation.
Blue DNA double helix breaking apart.
Keeping Telomeres in Their Places
Aparna Nathan, PhD | Apr 22, 2024 | 4 min read
New research reveals how cells prevent telomerase from meddling with double-stranded breaks.
Tapping Into Immunotherapy’s Potential to Help More People
Tapping into Immunotherapy’s Potential to Help More People
The Scientist Staff | 2 min read
Discover what researchers have learned about varying immunotherapy response rates between patients with the same cancer types.
Conceptual illustration of personalized medicine with medical icons next to a human face.
The Largest Whole-genome Sequencing Study in Cancer 
Danielle Gerhard, PhD | Apr 17, 2024 | 7 min read
Comprehensive genome sequencing of 13,880 tumors revealed somatic and germline mutations that could influence patient treatment and prognosis.
Two sister cells are seen in the foreground, while individual cells are seen behind them on a blue background.
Sister Cells Reveal Cancer’s Fate
Aparna Nathan, PhD | Apr 3, 2024 | 4 min read
A new method traces treatment resistant cells and predicts drugs that can make them more susceptible to cancer therapy.
Defining the Triple Negative Breast Cancer Morpholome
Defining the Triple Negative Breast Cancer Morpholome
The Scientist Staff | 1 min read
Learn how researchers take a phenotype-first approach to uncover hidden metastatic drivers at tissue and cellular levels.
Crystalline ball-and-stick model representation of a molecular structure.
Prioritizing PARylation in DNA Damage and Repair
The Scientist Staff | Apr 1, 2024 | 2 min read
Measuring cellular poly ADP-ribosylation can unlock new anticancer strategies and approaches.
An image of cells with the center stained green and some cells stained magenta over a black background.
Growing Milk-Secreting Mammary Organoids
Sneha Khedkar | Mar 29, 2024 | 3 min read
Mammary organoids derived from mouse embryonic stem cells could offer clues into mammary gland developmental origins and help researchers study breast cancer.
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