Crystalline ball-and-stick model representation of a molecular structure.
Prioritizing PARylation in DNA Damage and Repair
The Scientist Staff | Apr 1, 2024 | 2 min read
Measuring cellular poly ADP-ribosylation can unlock new anticancer strategies and approaches.
An image of cells with the center stained green and some cells stained magenta over a black background.
Growing Milk-Secreting Mammary Organoids
Sneha Khedkar | Mar 29, 2024 | 3 min read
Mammary organoids derived from mouse embryonic stem cells could offer clues into mammary gland developmental origins and help researchers study breast cancer.
Tapping Into Immunotherapy’s Potential to Help More People
Tapping into Immunotherapy’s Potential to Help More People
The Scientist Staff | 2 min read
Discover what researchers have learned about varying immunotherapy response rates between patients with the same cancer types.
A single channel splits into two micro-channels.
A Beating Heart on a Chip
Aparna Nathan, PhD | Mar 26, 2024 | 4 min read
Researchers used organ chips to mimic conditions that help heart cells mature.
Image showing monoclonal antibody treatment
The Resilience of Monoclonal Antibodies and their Makers
Laura Tran, PhD | Mar 15, 2024 | 10+ min read
The road to developing monoclonal antibodies for effectively targeting cancer was paved with tenacity, passion, and strokes of luck.
Defining the Triple Negative Breast Cancer Morpholome
Defining the Triple Negative Breast Cancer Morpholome
The Scientist Staff | 1 min read
Learn how researchers take a phenotype-first approach to uncover hidden metastatic drivers at tissue and cellular levels.
Infographic: Understanding CAR-T vs TCR Approaches
Danielle Gerhard, PhD | Mar 15, 2024 | 3 min read
Living drugs get a boost from emerging engineering strategies that focus on safety and specificity.
3D Rendering of Molecular Interaction in CAR Chimeric Antigen Receptor
Next-generation CAR and TCR Cancer Therapies
Danielle Gerhard, PhD | Mar 15, 2024 | 10+ min read
From smart receptors to novel biologics, scientists plan to overcome the challenges of treating solid tumors.
Epigenetic Influences and Mechanisms in Cancer
Epigenetic Influences and Mechanisms in Cancer
The Scientist Staff | 1 min read
In this webinar, Özgen Deniz and Christina Leslie will discuss how epigenetic regulation affects oncogenesis.
A needle drawing up fluid from an unlabeled vial.
Cancer Vaccination as a Promising New Treatment Against Tumors
Shelby Bradford, PhD | Mar 15, 2024 | 10+ min read
Vaccination has beaten back infections for more than a century. Now, it may be the next big step in battling cancer.
Robot hand holding glass sphere with glowing fiber neon communication wires
Gazing into Science’s Crystal Ball
Meenakshi Prabhune, PhD | Mar 15, 2024 | 3 min read
Basic research successes offer glimpses into future scientific advancements, but the outcomes are subject to change.
An Overview of High Throughput Screening
An Overview of High Throughput Screening
Tanvir Khan, PhD | 5 min read
High throughput screening (HTS) relies on liquid handling devices, robotics, plate readers, and data processing software to automatically test a large number of biological, genetic, chemical, or pharmacological samples. 
3D outline of a bone with red dots in the center.
Bringing Immunotherapy Straight to the Source
Aparna Nathan, PhD | Mar 14, 2024 | 4 min read
Engineered natural killer cells track down cancer cells in the bone marrow.
3D illustration of a lymphocyte in white and green.
A Quest for the Holy Grail of Cancer Targets
Danielle Gerhard, PhD | Mar 14, 2024 | 5 min read
Christopher Klebanoff hopes that his search for a small fraction of cancer-specific antigens will have a big impact on cancer cell therapies.
Hijacking Viruses: Optimizing Lentivirus-Based Cell Engineering
The Scientist | 1 min read
Filippo Rossignoli discusses the challenges he faced when employing lentiviruses to produce immunotherapies and how he overcame these obstacles.
Magnifying glass over a DNA sequence
A Science Sleuth Accuses a Harvard Medical School Neuroscientist of Research Misconduct
Danielle Gerhard, PhD | Feb 15, 2024 | 5 min read
Researchers await the outcome of an ongoing investigation into dozens of instances of alleged image problems spanning 29 publications over a period of 23 years.
Toppling the Genetic Dominoes in Bone Metastasis
Laura Tran, PhD | Feb 15, 2024 | 4 min read
A key gene that fuels the molecular cascade driving prostate cancer bone metastasis progression may open avenues for targeted therapies.
<h1 >Precision Medicine: A New Era in Cancer Therapy</h1>
Precision Medicine: A New Era in Cancer Therapy
Rebecca Roberts, PhD | 6 min read
Precision medicine helps clinicians tailor individual treatments, addressing genetic mutations, tumor microenvironment variations, and therapeutic resistance.
3D rendered image showing enhanced scanning electron micrograph of cancer cells.
Turning Off Metastasis in Breast Cancer
Nathan Ni, PhD | Feb 13, 2024 | 4 min read
An on-off enzyme switch controls metastasis in mice. 
All Roads Lead to Genome Editing
Danielle Gerhard, PhD | Feb 9, 2024 | 6 min read
Shondra Pruett-Miller has taken many paths in her career with her love of genome editing always as a guiding light.