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cancer

7 days ago | 4 min read

Skipping Toward Resistance: The Gradual Adaptation of Cancer Cells 

Instead of an on-off toggle switch, cancer cells adapt through a series of distinct states of increasing drug resistance.
Image of a cancer cell skipping across the water. 
This image shows hexagon shaped cells (mouse airway stem cells) that are outlined in magenta. Within each cell there are tiny dots that represent centrioles, which are colored cyan. 
Sep 6, 2024 | 4 min read

Introducing a New Version of the Cell Cycle

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A 3D render of multiple RNA strands floating around each other.
Improving RNA Sequencing with FFPE Samples
The Scientist Staff | Sep 2, 2024 | 2 min read
Samples are commonly stored in a way that degrades RNA. Scientists are devising new ways to overcome this obstacle for RNA sequencing. 
Pseudo-colored scanning electron microscope image of the algae microrobot with the algae in green and the drug-filled nanoparticles in orange.
Green Warriors: Algae Microrobots Set to Combat Metastasis
Laura Tran, PhD | Aug 26, 2024 | 4 min read
Green algae can be outfitted with nanoparticles, transforming them into efficient drug-delivering machines that target lung tumors.
A blue T cell attacks a blue cancer cell
Characterizing Cancer via the Immune Response
The Scientist | 1 min read
Researchers explore the immune system to further understand cancer and illuminate therapy development.
Cartoon image of floating transparent spheres with smaller blue spheres inside them.
Study Reveals a Cell-Eat-Cell World
Aparna Nathan, PhD | Aug 13, 2024 | 3 min read
From normal vertebrate development to tumor cell cannibalism, cell-in-cell events occur in many different contexts across the tree of life
Artistic rendering of a tumor cell as a misshapen purple blob, surrounded by spiky pink blobs representing NK cells.
Maintaining NK Cells’ Killer Instincts
Aparna Nathan, PhD | Aug 9, 2024 | 4 min read
A protein in natural killer cells keeps them from turning into more docile counterparts.
Exploring the Tumor Microenvironment with Spatial Biology
Exploring the Tumor Microenvironment with Spatial Biology
The Scientist Staff | 1 min read
In this webinar, Pinaki Bose and Fei Chen will discuss how scientists use spatial biology techniques to study the tumor microenvironment.
An illustration of circulating tumor cells surrounded by red blood cells.
Monitoring Multiple Myeloma Progression through Sequencing
Charlene Lancaster, PhD | Aug 2, 2024 | 4 min read
Irene Ghobrial sequences circulating tumor cells in blood samples to genomically profile patients with multiple myeloma.
A 3D rendering of an antibody drug conjugate with attached cytotoxic payloads.
Supporting Antibody-Drug Conjugate Development
The Scientist Staff | Aug 1, 2024 | 2 min read
Industry expertise helps scientists navigate and streamline antibody-drug conjugate research and development.
T-cell targeting cancer cells
Cell-Based Assays for Immuno-Oncology
Lonza | 1 min read
Cellular immunogenicity and immunotoxicity assays help scientists design, validate, and translate therapeutic research into treatments that weaponize the immune response against cancer.
A melanoma on human skin.
Minicells Shut Down Cancer’s Spread 
RJ Mackenzie | Jul 29, 2024 | 4 min read
A nutrient-based nanomedicine stopped runaway tumor growth in mice by firing up a latent metabolic pathway.
A fluorescent imaginal disc from <em >Drosophila&nbsp;</em>larvae on a black background.
Cancers with an Exceptional Cause
Kamal Nahas, PhD | Jul 18, 2024 | 4 min read
Epigenetic control of gene expression can switch on genes that push cell division into overdrive independently of genetic faults.
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Understanding the Effects of Extrachromosomal DNA on Cancer
The Scientist | 1 min read
Lukas Chavez uses multiomic techniques to study how extrachromosomal DNA (ecDNA) contributes to tumor heterogeneity and gene expression changes in medulloblastoma.
A hand holding a pill against sunlight.
Vitamin D Acts via the Microbiome to Boost Cancer Immunity
Nicholas Miliaras, PhD | Jul 12, 2024 | 4 min read
An essential nutrient and the gut flora, thought to have separate but important roles in the immune response, join forces.
A hand holding forceps grabs a cryopreserved tube.&nbsp;
The Evolution of Biobanking and its Role in Precision Oncology
Abhishek Mohanty, PhD | Jul 1, 2024 | 6 min read
Biobanks fuel the multiomics-based practice of personalized oncomedicine and cancer biomarker discovery.
Gloved hand holding miniature organ models
From the Expert: Júlia Crispim da Fontoura on 3D Cell Cultures
The Scientist | 1 min read
Júlia Crispim da Fontoura explains how researchers grow different types of 3D cell cultures.
Cartoon of a scientist kneeling over a broken sample tube on the floor.
Crushing ChIP Like Never Before
Shelby Bradford, PhD | Jul 1, 2024 | 2 min read
A wayward lab chair ended three days of work in a single footfall for Elinne Becket.
Microscopy image of hepatocytes stained in pink with purple nuclei.
Liver Proteins Keep T Cells Out of Tumors
Aparna Nathan, PhD | Jun 21, 2024 | 4 min read
A new study finds an unexpected role for hepatocytes in anticancer immunity.
An illustration of cells growing in the presence of cytokines.
Advancing Immunotherapy Development with High-Quality Cytokines
The Scientist and Sino Biological | 3 min read
Superior quality cytokines are crucial for reliable research results and the safe production of cancer cell therapies.
Three images of a hand with an abrasion progressing from most recently injured (left) to most healed (right).
Stem Cell Plasticity: A Double-Edged Sword
Hannah Thomasy, PhD | Jun 14, 2024 | 5 min read
Yejing Ge explores the behavior of skin-resident stem cells in wound repair, cancer, and aging.
Four circular maps of color-coded immune cell types corresponding to the four tumor microenvironment archetypes.
A Bird’s Eye View of the Tumor Microenvironment
Kamal Nahas, PhD | Jun 3, 2024 | 3 min read
Immune cells form different communities throughout a tumor, potentially disrupting how cancers respond to treatments.
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