CRISPR Gene Editing Deletes, Shuffles More Genes than Intended
The DNA-cutting enzyme used in the technique is not as precisely targeted as scientists had thought, and investors take notice.
CRISPR Gene Editing Deletes, Shuffles More Genes than Intended
CRISPR Gene Editing Deletes, Shuffles More Genes than Intended

The DNA-cutting enzyme used in the technique is not as precisely targeted as scientists had thought, and investors take notice.

The DNA-cutting enzyme used in the technique is not as precisely targeted as scientists had thought, and investors take notice.

cancer, immunology
Traitorous Tumor Cells Kill Their Own Kind
Traitorous Tumor Cells Kill Their Own Kind
Ruth Williams | Jul 11, 2018
Researchers plan to turn cancer cells into defectors, engineering them to kill the tumors from whence they came, and have tested the approach in mice.
Natural Killer Cells Prove Effective as a CAR Therapy in Mice
Natural Killer Cells Prove Effective as a CAR Therapy in Mice
Katarina Zimmer | Jul 6, 2018
Stem-cell–derived natural killer cells engineered in a similar way to CAR-T cells may pave the way to “off the shelf” cancer therapies that aren’t patient-specific.
Amazonians Offer Clues to Human Childhood Development
Amazonians Offer Clues to Human Childhood Development
Shawna Williams | Jul 1, 2018
A study of Shuar children in Ecuador provides a window into how the human body responds to infection in the sorts of conditions that shaped our species’ evolution.
Opinion: Deductive Science Is Needed for Public Health
Opinion: Deductive Science Is Needed for Public Health
Giuseppe Carruba | Jun 27, 2018
Big data and empirical approaches to understanding diseases provide a limited picture of pathogenesis.
Artificial Intelligence to Boost Liquid Biopsies
Artificial Intelligence to Boost Liquid Biopsies
Claire Asher | Jun 26, 2018
Machine-learning algorithms tuned to detecting cancer DNA in the blood could pave the way for personalized cancer care.
Laxative Causes Long-Term Changes to Mouse Microbiome
Laxative Causes Long-Term Changes to Mouse Microbiome
Abby Olena | Jun 14, 2018
Acute bouts of diarrhea could have lasting effects on the microbiota and host immune system activation, a mouse study suggests.
This Flu Season Killed 172 Kids
This Flu Season Killed 172 Kids
Sukanya Charuchandra | Jun 11, 2018
Vaccination reduced the risk of death by two-thirds for children with no other health problems.  
CRISPR Efficiency Tied to Cancer-Causing Process
CRISPR Efficiency Tied to Cancer-Causing Process
Kerry Grens | Jun 11, 2018
Two studies find the genome-editing technique works best when cells have a faulty DNA-damage response that’s frequently present in cancers.  
EPA to Limit Assessments of Toxic Chemical Risks
EPA to Limit Assessments of Toxic Chemical Risks
Ashley Yeager | Jun 8, 2018
Reducing the evaluation to only direct contact, rather than including environmental exposures, could leave damaging substances on the market, critics say.