cell biology

Coaxing bacteria into taking up recombinant DNA was arduous until Douglas Hanahan took action.

Bacteria cooperate to benefit the collective, but cheaters can rig the system. How is the balance maintained?

From spatial structuring to policing, cooperative bacteria have a wide toolkit to contain the spread of cheaters.

This new understanding could one day lead to targeted treatments. 

mRNA-encoded self-assembling enveloped virus-like particles presenting SARS-CoV-2 spike protein enhance immunity and may provide better protection against viral variants. 

Gaining a better understanding of the dynamic and reciprocal interactions between cancer cells and the tumor microenvironment is essential for improving patient diagnosis and treatment.

A novel, non-invasive treatment using electrical currents exploits physiological properties of dividing cancer cells to prolong survival and augment current therapies.

By mechanically inducing the expansion of cranial sutures in young adult mice, researchers stimulated stem cell proliferation that is key to healing bone injuries.

In a bid to address safety concerns about immune reactions during treatment with CRISPR-based therapeutics, a new technique speeds up how quickly the body destroys the DNA-cutting enzyme Cas9.

A new study relying on DNA methylation clocks suggests that the biological age of mouse and human cells can fluctuate in response to stressful events.

Researchers repurpose tiny bacterial injection systems to specifically inject a wide variety of proteins into human cells and living mice.

The mutation prevents certain amino acids from entering neurons, causing the cells to die early in development.

Engineering of a novel device to treat T1D, featuring local immunosuppression and a vascularized cell reservoir to prolong islet cell survival.

Immune cells and pain neurons form complex partnerships to protect our bodies from pathogens, new research reveals.