Years of Prozac Alter Lipids in Young Monkeys’ Brains: Study
Years of Prozac Alter Lipids in Young Monkeys’ Brains: Study
James M. Gaines | Sep 10, 2021
Long-term administration of the antidepressant fluoxetine was tied to decreased concentrations of about 100 different brain lipids in adolescent macaques, hinting at a potential mechanism underlying the drug’s rare but severe side effects.
Signaling Dynamics Fine-Tune Gene Expression
Signaling Dynamics Fine-Tune Gene Expression
Ruth Williams | Sep 3, 2021
The dynamic behavior of a transcriptional activator can be used to specify the activity level of its target gene, a study suggests.
Infographic: A Yeast Model for Studying Histone Modifications
Infographic: A Yeast Model for Studying Histone Modifications
Amanda Heidt | Sep 1, 2021
The methodology involves modifying histones and displaying them on the cell surface for analysis.
Yeast “Mini Labs” Help Researchers Probe Histone Modifications
Yeast “Mini Labs” Help Researchers Probe Histone Modifications
Amanda Heidt | Sep 1, 2021
By harnessing a unique property of yeast, scientists can synthesize histones and the enzymes that modify these proteins, which spool DNA and influence gene expression.
Cell Biologist David Sabatini Fired for Sexual Harassment
Cell Biologist David Sabatini Fired for Sexual Harassment
Shawna Williams | Aug 22, 2021
The researcher, known for his work on the mTOR signaling pathway, is no longer with MIT’s Whitehead Institute or HHMI following an investigation into his conduct.
Fat Cells Send Mitochondrial Distress Signals to the Heart
Fat Cells Send Mitochondrial Distress Signals to the Heart
Ruth Williams | Aug 20, 2021
Vesicles containing fragments of the organelles released from stressed adipocytes protect the heart against oxygen deprivation, a study in mice shows.
Cellular Biologist Michael Mueckler Dies at 67
Cellular Biologist Michael Mueckler Dies at 67
Lisa Winter | Aug 18, 2021
His work centered on the mechanisms of glucose transport into cells.
Antibodies Stop Sperm in Their Tracks
Antibodies Stop Sperm in Their Tracks
Abby Olena | Aug 11, 2021
Engineered antibodies trap and immobilize human sperm in the reproductive tract of female sheep, paving the way for possible use as a nonhormonal contraceptive in people.
Fat Tissue Reorganizes During Pregnancy
Fat Tissue Reorganizes During Pregnancy
Catherine Offord | Aug 1, 2021
Researchers identify a protein that promotes changes in adipose tissue in vitro and in pregnant mice and may help protect against gestational diabetes in humans.
Infographic: How Pregnancy Changes Fat Tissue
Infographic: How Pregnancy Changes Fat Tissue
Catherine Offord | Aug 1, 2021
Researchers propose a mechanism by which a protein produced in the placenta may trigger blood vessel growth and enlarge fat cells.
Predictions of Most Human Protein Structures Made Freely Available
Predictions of Most Human Protein Structures Made Freely Available
Lisa Winter | Jul 23, 2021
The AlphaFold program from AI firm DeepMind has amassed a huge database of protein structures from humans and model organisms.
Humans Can Survive Without Key Autophagy Gene
Humans Can Survive Without Key Autophagy Gene
Annie Melchor | Jul 19, 2021
Loss of the protein ATG7 is fatal in mice, but not always for people—although it is linked to human neurodevelopmental disorders, researchers report.
Stress Paralyzes Immune Cells
Stress Paralyzes Immune Cells
Emma Yasinski | Jul 1, 2021
Scientists show that an influx of noradrenaline can halt immune cells in mice.
Izzy Jayasinghe Harnesses Cutting-Edge Microscopy to Image Cells
Izzy Jayasinghe Harnesses Cutting-Edge Microscopy to Image Cells
Shawna Williams | Jul 1, 2021
The University of Sheffield researcher devises new protocols to gain molecular-level insights.