Red Blood Cells Activate Innate Immune System
Red Blood Cells Activate Innate Immune System
Abby Olena | Oct 20, 2021
Researchers link the ability of the cells to bind and present DNA from pathogens and cell death to anemia, which is common in COVID-19, and immune activation.
Genetic Risks for Depression Differ Between Ancestral Groups
Genetic Risks for Depression Differ Between Ancestral Groups
Chloe Tenn | Oct 19, 2021
A large genome-wide association study in East Asians uncovers novel genetic links to depression, calling attention to the consequences of underrepresentation of non-European groups in genetic research data.
Henrietta Lacks Estate Sues Thermo Fisher over HeLa Cell Line
Henrietta Lacks Estate Sues Thermo Fisher over HeLa Cell Line
Catherine Offord | Oct 4, 2021
Attorneys for the family seek compensation for the company’s sale of cells cloned from tissue removed without consent by doctors at Johns Hopkins Hospital 70 years ago.
Infographic: Modeling Neurodegenerative Diseases with Yeast
Infographic: Modeling Neurodegenerative Diseases with Yeast
Mahlon Collins | Oct 1, 2021
Conservation of structures and functions between single-celled fungi and human cells allow researchers to probe the brain.
Experiment Gone Awry Suggests Novel Way to Combat Hypoxia
Experiment Gone Awry Suggests Novel Way to Combat Hypoxia
Phil Jaekl | Oct 1, 2021
While exploring suspended animation in mice, scientists discover how an enzyme can protect the brain from dangerously low levels of oxygen.
Yeast Models Provide New Insights into Neurodegenerative Diseases
Yeast Models Provide New Insights into Neurodegenerative Diseases
Mahlon Collins | Oct 1, 2021
The single-celled fungus allows researchers to study Alzheimer’s, Parkinson’s, ALS and other brain diseases with unparalleled speed and scale.
Blind Mole Rats Use Junk DNA to Combat Cancer
Blind Mole Rats Use Junk DNA to Combat Cancer
Ruth Williams | Sep 30, 2021
Activation of retrotransposons in the animals’ cancerous cells sets off an innate immune response that triggers cell death.
DNA in Cell Cytoplasm Implicated in Age-Related Blindness
DNA in Cell Cytoplasm Implicated in Age-Related Blindness
Katarina Zimmer | Sep 29, 2021
A new study suggests that DNA synthesized in the cell cytoplasm drives retinal cell death in an advanced form of age-related macular degeneration, a leading cause of blindness.
DNA Methylation Influences Replication and Genome Organization
DNA Methylation Influences Replication and Genome Organization
Abby Olena | Sep 22, 2021
A study links the loss of DNA methylation across the genome—as is common in cancer—to the disruption of the 3-D compartments that organize the genome and to the timing of DNA replication.
Morphine Tolerance Pathway Identified in Mice
Morphine Tolerance Pathway Identified in Mice
David Adam | Sep 20, 2021
Prolonged exposure to morphine triggers cells in the spine to release signaling molecules that increase pain sensitivity and dull the relief of the drug. Blocking this activity could improve pain management.
Accurate Protein Production Promotes Longevity
Accurate Protein Production Promotes Longevity
Ruth Williams | Sep 15, 2021
Worms, flies, and yeast live longer if the fidelity of their protein-making machinery is improved, a study shows.
Years of Prozac Alter Lipids in Young Monkeys’ Brains: Study
Years of Prozac Alter Lipids in Young Monkeys’ Brains: Study
James M. Gaines | Sep 10, 2021
Long-term administration of the antidepressant fluoxetine was tied to decreased concentrations of about 100 different brain lipids in adolescent macaques, hinting at a potential mechanism underlying the drug’s rare but severe side effects.
Signaling Dynamics Fine-Tune Gene Expression
Signaling Dynamics Fine-Tune Gene Expression
Ruth Williams | Sep 3, 2021
The dynamic behavior of a transcriptional activator can be used to specify the activity level of its target gene, a study suggests.
Infographic: A Yeast Model for Studying Histone Modifications
Infographic: A Yeast Model for Studying Histone Modifications
Amanda Heidt | Sep 1, 2021
The methodology involves modifying histones and displaying them on the cell surface for analysis.