Melanocyte stem cells are shown in red and other cell nuclei are shown in blue.
Hair Turns Gray Due to Stuck Stem Cells
Mariella Bodemeier Loayza Careaga, PhD | Sep 8, 2023 | 3 min read
Hair-coloring stem cells must swing back and forth between their maturity states to give hair its color.
Illustration showing origami tardigrade, fungi and bacteria.
Magnifying Curiosity with a Pocket Microscope
Danielle Gerhard, PhD | Sep 8, 2023 | 5 min read
Microscopes were inaccessible to most of the world until Manu Prakash and Jim Cybulski put their engineering prowess to the test.
Modeling Human Disease and Development with Organoids
Modeling Human Disease and Development with Organoids
The Scientist’s Creative Services Team | 1 min read
Discover how scientists use cardiac and skin organoids to study differentiation and toxicity. 
Infographic showing the selective strengthening of synapses that received stimulation.
Infographic: Synaptic Plasticity in the Sea Slug
Danielle Gerhard, PhD | Sep 8, 2023 | 1 min read
The sea slug has helped scientists in their quest to understand how neurons encode memories.
The image shows six different panels containing cells. On each panel, the cells are labelled using a different fluorescent dye that highlights features of a specific organelle within the cells.
Cell Painting: Exploring the Richness of Biological Images
Mariella Bodemeier Loayza Careaga, PhD | Sep 8, 2023 | 4 min read
By coloring different organelles simultaneously, cell painting allows scientists to pick up subtle changes in cell function in response to drugs and other perturbations.
Discover the Freshness of Frozen PBMCs
Discover the Freshness of Frozen PBMCs
The Scientist’s Creative Services Team | 1 min read
Researchers discuss how peripheral blood mononuclear cell (PBMC) cryopreservation affects T cell activation and immune cell phenotypes.
Infographic: Beyond the Nucleus: mRNA Localization in Neurons
Danielle Gerhard, PhD | Sep 8, 2023 | 1 min read
To support thousands of incoming connections, neurons use sophisticated transportation networks for delivering mRNA to faraway regions.
Infographic detailing two volume electron microscopy modalities.
Infographic: Drivers of the Expansion of Volume Electron Microscopy
Danielle Gerhard, PhD | Sep 8, 2023 | 2 min read
Technological advancements over the last two decades transformed volume electron microscopy, improving usability, resolution, and throughput.
Sino Biological 
Introducing GMP-Grade Recombinant Cytokines for Stem Cell Research
The Scientist’s Creative Services Team and Sino Biological | 3 min read
Cutting edge technology delivers cytokines with high purity, high bioactivity, high batch-to-batch consistency, and high stability.
This image depicts the fruit fly nerve cord connectome. It highlights 930 neurons, a subset of the full set of reconstructed neurons.
The Expansion of Volume Electron Microscopy
Danielle Gerhard, PhD | Sep 8, 2023 | 6 min read
A series of technological advancements for automation and parallel imaging made volume electron microscopy more user friendly while increasing throughput.
A rendering of a human brain in blue on a dark background with blue and white lines surrounding the brain to represent the construction of new connections in the brain.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD | Sep 8, 2023 | 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
A prism dispersing sunlight, splitting into a spectrum on a white background.
Shining a Light on New Microscopy Technologies
The Scientist’s Creative Services Team and Evident | 3 min read
Scientists turn to technological advances that streamline microscopy workflows and enable life science breakthroughs.
A fluorescence microscopy image of a common mouse ear with a black background, an embedded bead visible as a white circle, and regenerating tissue around it shown in green.
Mice Heal Themselves in Response to a Common Signaling Molecule
Ida Emilie Steinmark, PhD | Sep 8, 2023 | 4 min read
A newly discovered way to induce scarless healing in mice depends on a highly conserved signaling pathway that is also present in humans.
Woman smiling at the camera working out on a blue yoga mat.
Keeping Older Muscles Strong
Hannah Thomasy, PhD, Drug Discovery News | Sep 5, 2023 | 5 min read
From stem cell-recruiting gels to hormone cycle restoration, Tracy Criswell has big ideas about how to combat age-related decline in muscle regeneration.
A microscopy image of an apical-out colon organoid that was produced using MilliporeSigma’s protocol.
Turning Organoids Inside Out 
The Scientist’s Creative Services Team, MilliporeSigma, and Hub Organoids | 4 min read
Discover how a new procedure reverses the polarity of typical basolateral-out organoids to form versatile apical-out organoids.
Illustration of a group scientists in medical or chemical laboratory.
From Mentee to Mentor: Teaching Undergraduates in the Lab
Danielle Gerhard, PhD | Sep 1, 2023 | 2 min read
Mark Emerson shares his secret for establishing a fruitful research experience for students and mentors alike.
Infographic showing the difference between the classic MINFLUX and the updated MINFLUX
A New Kind of MINFLUX
Ida Emilie Steinmark, PhD | Sep 1, 2023 | 1 min read
MINFLUX brought record-breaking resolution to fluorescence microscopy in 2016. A new version perfected for protein tracking came out this spring.
A 3D rendering of an albumin’s protein structure.
Providing Stability In Vivo, In Vitro, and In Culture
The Scientist’s Creative Services Team and MilliporeSigma | 3 min read
Albumins enable researchers to bind, sequester, and stabilize important molecules across research applications.
A graph showing how scGPT groups cells, each represented as a dot, into cell types, shown as clusters of dots of the same color.
A New AI Tool Predicts Gene Expression in a Single Cell
Carissa Wong, PhD | Aug 21, 2023 | 4 min read
An artificial intelligence tool, scGPT, can identify cell types, predict the effects of disrupting genes, and pinpoint which genes interact with each other.
Conceptual image of hair loss showing trees in the shape of a human head at various seasonal stages of shedding their leaves.
Islands of Knowledge: Hairy Skin Moles Make Their Mark
Iris Kulbatski, PhD | Aug 7, 2023 | 3 min read
Skin moles that sprout thick, long hairs produce signaling molecules that stimulate hair follicle stem cells to initiate new hair growth. This discovery may make baldness a thing of the past.