Microscopy image of green and red neurons in a blue section of cortex.
Engineered Rabies Virus Illuminates Neural Circuitry
Hannah Thomasy, PhD | Jun 14, 2024 | 10+ min read
Scientists turned a deadly virus into a crucial tool for understanding the wiring of the brain.
<em>T</em><em >rypanosoma brucei</em> parasites.
A Voyage of Curiosity and Vision
Mariella Bodemeier Loayza Careaga, PhD | Jun 14, 2024 | 9 min read
Parasitologist Luísa Figueiredo uncovered key elements of the secret life of African trypanosomes inside their hosts.
Gloved hand holding miniature organ models
From the Expert: Júlia Crispim da Fontoura on 3D Cell Cultures
The Scientist | 1 min read
Júlia Crispim da Fontoura explains how researchers grow different types of 3D cell cultures.
Infographic showing how flow cytometry enables researchers to assess several cell parameters simultaneously at a single-cell level with the help of lasers.
Flow Cytometry: Scattering Light to Measure Cells
Shelby Bradford, PhD | Jun 14, 2024 | 2 min read
Scientists analyze and quantify characteristics of cells and other particles with the power of lasers.
Stem cells are compressed into a ball (green) by a C-shaped biobot (red).
From Code to Creature
Laura Tran, PhD | Jun 14, 2024 | 10+ min read
A happenstance collaboration between biologists and roboticists led to the birth of a strange creation: living machines derived from frog stem cells.
An illustration of cells growing in the presence of cytokines.
Advancing Immunotherapy Development with High-Quality Cytokines
The Scientist and Sino Biological | 3 min read
Superior quality cytokines are crucial for reliable research results and the safe production of cancer cell therapies.
A chromosome is gradually unwinding until the DNA double helix is visible. Proteins interact with parts of the DNA. Antibodies are attached to these protein-DNA interacting regions.
Chromatin Immunoprecipitation Reveals DNA-Protein Interactions
Mariella Bodemeier Loayza Careaga, PhD | Jun 14, 2024 | 10 min read
Proteins interact with DNA to regulate many vital processes in cells. Nearly 40 years ago, researchers developed a way to map these molecular connections.
A cell with gold particles inside is hit with a red laser.
How Flow Cytometry Spurred Cell Biology
Shelby Bradford, PhD | Jun 14, 2024 | 10+ min read
The ability to rapidly count and measure features of cells opened the research flood gates.
3D illustration depicting white and red blood cells flowing in a network of blood vessels.
How Migrating Cells Navigate Biological Mazes
Laura Mac-Daniel, PhD | 4 min read
A key protein that detects changes in plasma membrane curvature guides immune-like cells through environmental obstacles.
Photo of a line of grassy plants with the roots under the soil visible.
Plants Defend Themselves Against Heavy Metals
Shelby Bradford, PhD | Jun 13, 2024 | 3 min read
A metabolite from maize roots protects the plants against arsenic toxicity.
Fluorescent microscopy image with a black background and blue, green, and red colors marking different cells.
A Safe-Haven for Intestinal Viruses
Aparna Nathan, PhD | Jun 11, 2024 | 4 min read
A rare gut cell puzzles researchers by avoiding immune cells.
Optimizing Organoid Culture for Development and Disease Modeling
Optimizing Organoid Culture for Development and Disease Modeling
The Scientist Staff | 1 min read
Discover how to grow mini-organs for the advanced investigation of in vivo processes.
Microscopy image of an ovary labeled with blue, green, and yellow fluorescent markers.
A Cellular Roadmap for Fertility
Aparna Nathan, PhD | Jun 6, 2024 | 4 min read
Researchers created a spatial atlas of rare cell types in the ovaries.
A 3D microscopic image of a heart tissue section with cardiac myocytes and macrophages.
Taking Out the Trash: An Alternative Cellular Disposal Pathway
Charlene Lancaster, PhD | Jun 6, 2024 | 4 min read
Researchers reveal that cellular secretion removes defective mitochondria when lysosomes are dysfunctional.
A scientist cultures organoids in a multi-well plate filled with red cell culture media
Understanding the 3D Cell Culture Revolution
Rebecca Roberts, PhD | 6 min read
3D cell culture techniques closely mimic in vivo conditions, generating more accurate data for disease modeling and drug toxicity testing.
A scientist examining a microtiter plate
Tips for Optimizing Cell-Based Readouts
The Scientist Staff | Jun 3, 2024 | 2 min read
Explore five tips for improving detection and reducing background noise with cell-based fluorescence measurements on microplate readers.
Concept illustration of the placenta
Shifting Parturition Perspectives in Perinatology Research
Deanna MacNeil, PhD | Jun 3, 2024 | 1 min read
Nardhy Gómez-López investigates the placental immunology of preterm birth.
<em >The Scientist</em>&rsquo;s Journal Club: Neuroscience and Cell Biology
The Scientist’s Journal Club: Neuroscience and Cell Biology
The Scientist Staff | 1 min read
Scientists discuss their latest findings on cell secretory states, synapse formation, and neurodegenerative disease.
Larger green cell with two cyan spots and many smaller magenta circles in and around the cell.&nbsp;
Synthetic Systems for Studying Natural Cells
Danielle Gerhard, PhD | Jun 3, 2024 | 2 min read
Oskar Staufer engineers synthetic systems to explore cancer biology.
A Hydractinia polyp with stinging cells shown in red throughout the body and the tentacles.
With Neither Brains nor Brawn, Jellyfish and Relatives Developed Subcellular Weapons Instead
Hannah Thomasy, PhD | May 29, 2024 | 6 min read
Anna Klompen explained how cnidarian stinging cells harpooned their way into her heart and could help answer fundamental questions in biology.