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Patient Registries to Bolster Cell- and Gene-Therapy Clinical Trial Data
Anna Azvolinsky | May 15, 2018
As the first personalized cell and gene therapies are approved from small clinical trials, researchers propose the creation of publicly accessible databases to pull together real-world results.
World’s Largest Cell and Gene Therapy Plant Opens
Catherine Offord | Apr 11, 2018
Lonza will employ more than 200 full-time staff to work at the Texas-based facility, the company says.
Partial Reprogramming Offers a Way to Generate High Volumes of Progenitor-Like Cells
Abby Olena | Nov 30, 2017
Activating genes for reprogramming factors for a short time transforms large numbers of differentiated cells into multipotent forms that could be useful for cell-based therapies.
New CAR T-Cell Therapy Shows Promise in Trial for Leukemia
Katarina Zimmer | Nov 21, 2017
The immunotherapy, which targets CD22 on cancer cells rather than CD19, might prove useful in patients for whom previous T-cell treatments were unsuccessful.
Child Receives Transgenic Skin Over Most of His Body
Ruth Williams | Nov 8, 2017
A combination gene-and-cell therapy has given a boy with a grievous skin disease a new lease on life, and has resolved a dermatology debate to boot.
FDA Approves Second CAR T-Cell Therapy
Ashley P. Taylor | Oct 19, 2017
The therapy, produced by Kite Pharma and owned by Gilead Sciences, is approved for use against some types of large B-cell lymphomas.
Synthetic Stem Cells Regenerate Heart Tissue in Mice
Diana Kwon | Jun 1, 2017
These engineered “cells” were made from the secretions and membranes of human mesenchymal stem cells.
Infographic: How to Make an Artificial Stem Cell
Diana Kwon | May 31, 2017
See researchers' recipe for synthetic mesenchymal stem cells, which showed cardiac regenerative potential in mice.
New FDA Pathway to Accelerate Development of Cell Therapies
Jef Akst | May 22, 2017
Four products have already qualified for the regenerative medicine advanced therapy (RMAT) designation that provides extra interactions with the agency, and sooner.
Cell Lines Gain Cancer-Related Mutations
Kerry Grens | Apr 27, 2017
A screen of human embryonic stem cell lines finds several that accumulated changes in the gene
including aberrations commonly seen in cancer.