cholesterol
Crystal Structure, Murky Function
Crystal Structure, Murky Function
Ruth Williams | Jan 29, 2015
Scientists have determined the crystal structures of bacterial translocator proteins, but their functions remain unclear.
Mutation Tied to Reduced Heart Disease
Mutation Tied to Reduced Heart Disease
Kerry Grens | Jun 20, 2014
Genetic variants that cripple a triglyceride-producing protein are linked with a lower risk of heart attack and stroke.
Path Finding
Path Finding
Abby Olena | Mar 1, 2014
Biochemistry reveals the missing link in a pathway that archaea and some bacteria use to generate essential compounds.
RNAi Remedy Lowers Cholesterol
RNAi Remedy Lowers Cholesterol
Abby Olena | Oct 3, 2013
A Phase 1 clinical trial demonstrates the safety and efficacy of an siRNA-based, cholesterol-lowering drug.
Obesity-Fighting Drug May Improve Metabolism
Obesity-Fighting Drug May Improve Metabolism
Erin Weeks | Sep 3, 2013
Initial tests of a hormone therapy suggest it reduces LDL cholesterol and improves weight loss in obese patients with type 2 diabetes.
Gene a Pain for Statin Users
Gene a Pain for Statin Users
Kate Yandell | Aug 28, 2013
A genetic variant may help explain why some patients experience muscle discomfort and dysfunction while taking the cholesterol-lowering medications.
Epigenetic Drug Improves Cholesterol Levels
Edyta Zielinska | Aug 28, 2012
Results from a Phase II trial for cardiovascular disease with an epigenetic target therapy show promise.
Lipitor Patent Expires
Cristina Luiggi | Nov 30, 2011
The pharmaceutical darling that has brought billions in revenue to Pfizer over the past 15 years will now share the shelves with its generic competitors.