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Crystal Structure, Murky Function
Ruth Williams | Jan 29, 2015
Scientists have determined the crystal structures of bacterial translocator proteins, but their functions remain unclear.
Mutation Tied to Reduced Heart Disease
Kerry Grens | Jun 20, 2014
Genetic variants that cripple a triglyceride-producing protein are linked with a lower risk of heart attack and stroke.
Abby Olena | Mar 1, 2014
Biochemistry reveals the missing link in a pathway that archaea and some bacteria use to generate essential compounds.
RNAi Remedy Lowers Cholesterol
Abby Olena | Oct 3, 2013
A Phase 1 clinical trial demonstrates the safety and efficacy of an siRNA-based, cholesterol-lowering drug.
Obesity-Fighting Drug May Improve Metabolism
Erin Weeks | Sep 3, 2013
Initial tests of a hormone therapy suggest it reduces LDL cholesterol and improves weight loss in obese patients with type 2 diabetes.
Gene a Pain for Statin Users
Kate Yandell | Aug 28, 2013
A genetic variant may help explain why some patients experience muscle discomfort and dysfunction while taking the cholesterol-lowering medications.
Epigenetic Drug Improves Cholesterol Levels
Edyta Zielinska | Aug 28, 2012
Results from a Phase II trial for cardiovascular disease with an epigenetic target therapy show promise.
Lipitor Patent Expires
Cristina Luiggi | Nov 30, 2011
The pharmaceutical darling that has brought billions in revenue to Pfizer over the past 15 years will now share the shelves with its generic competitors.