chronic pain, immunology, developmental biology
Prizes and Penalties
Prizes and Penalties
Bob Grant | Jan 1, 2018
Life is filled with pleasure and pain. Science and society are struggling mightily with both.
Targeting Sodium Channels for Pain Relief
Targeting Sodium Channels for Pain Relief
Catherine Offord | Jan 1, 2018
The race to develop analgesic drugs that inhibit sodium channel NaV1.7 is revealing a complex sensory role for the protein.
Glial Ties to Persistent Pain
Glial Ties to Persistent Pain
Mark R. Hutchinson | Jan 1, 2018
Immune-like cells in the central nervous system are now recognized as key participants in the creation and maintenance of persistent pain.
Painful Realities
Painful Realities
The Scientist Staff | Dec 31, 2017
Dave Thomas, a researcher at the National Institute on Drug Abuse, talks about the harsh truths and frustrating complexity of pain and analgesia.
Infographic: A Painful Pathway
Infographic: A Painful Pathway
Catherine Offord | Dec 31, 2017
Since the mid-2000s, the voltage-gated sodium channel NaV1.7 has emerged as a promising target for a new class of analgesics.
Infographic: Two Pain Paths Diverge in the Body
Infographic: Two Pain Paths Diverge in the Body
Mark R. Hutchinson | Dec 31, 2017
The acute pain that results from injury or disease is very different from chronic pain.
Thousands of Mutations Accumulate in the Human Brain Over a Lifetime
Thousands of Mutations Accumulate in the Human Brain Over a Lifetime
Ruth Williams | Dec 7, 2017
Single-cell genome analyses reveal the amount of mutations a human brain cell will collect from its fetal beginnings until death.
Antiviral Immunotherapy Comes of Age
Antiviral Immunotherapy Comes of Age
Lucas Laursen | Dec 4, 2017
T-cell therapies are not just for cancer. Researchers are also advancing immunotherapy methods to protect bone marrow transplant patients from viral infections. 
Passing the Torch
Passing the Torch
Mary Beth Aberlin | Dec 1, 2017
Looking back, looking forward
Immune System Targets Diverse Viruses Using the Same Small Peptide
Immune System Targets Diverse Viruses Using the Same Small Peptide
Catherine Offord | Dec 1, 2017
A single receptor on natural killer cells recognizes an amino acid sequence conserved across Zika, dengue, and related pathogens.