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Toward a Nonaddictive Opioid
Ben Andrew Henry | Aug 18, 2016
A newly discovered painkiller does not cause respiratory depression or addiction in mice and could be an alternative to frequently abused prescription medicines, researchers report.
Blocking a Stress-Related Gene Relieves Chronic Pain
Anna Azvolinsky | Feb 10, 2016
Inhibiting the activity of a protein involved in the body’s stress response can ease chronic pain in mice.
Week in Review: May 19–23
Tracy Vence | May 23, 2014
Sperm-sex–sensing sows; blocking a pain receptor extends lifespan in mice; stop codons can code for amino acids; exploring the tumor exome
No Pain, Big Gain
Kate Yandell | May 22, 2014
Eliminating a pain receptor makes mice live longer and keeps their metabolisms young.
Pain and Progress
Kerry Grens | Feb 1, 2014
Is it possible to make a nonaddictive opioid painkiller?
Centipede Venom Tops Morphine
Kerry Grens | Oct 1, 2013
The substance targets the same ion channel that's mutated in people who don't feel pain.
Natural Opioids Linked to Chronic Pain
Jef Akst | Sep 19, 2013
The body’s own pain-quelling system may be at the root of chronic pain and symptoms of opioid withdrawal, according to a new study in mice.
From Toxins to Therapeutics
Dan Cossins | Mar 19, 2013
Researchers are finding new drugs for chronic pain and autoimmune diseases by modifying animal venom-derived molecules that target the nervous and immune systems.
Ed Yong | May 23, 2012
Neurons injected into mice help treat chronic pain at its roots, rather than simply alleviating its symptoms.
Metabolites Involved in Chronic Pain
Jeffrey M. Perkel | Jan 22, 2012
Untargeted metabolic profiling implicates a new suite of metabolites that may be involved in nerve damage-induced pain.