chronic pain
Toward a Nonaddictive Opioid
Toward a Nonaddictive Opioid
Ben Andrew Henry | Aug 18, 2016
A newly discovered painkiller does not cause respiratory depression or addiction in mice and could be an alternative to frequently abused prescription medicines, researchers report.
Blocking a Stress-Related Gene Relieves Chronic Pain
Blocking a Stress-Related Gene Relieves Chronic Pain
Anna Azvolinsky | Feb 10, 2016
Inhibiting the activity of a protein involved in the body’s stress response can ease chronic pain in mice.
Week in Review: May 19–23
Week in Review: May 19–23
Tracy Vence | May 23, 2014
Sperm-sex–sensing sows; blocking a pain receptor extends lifespan in mice; stop codons can code for amino acids; exploring the tumor exome
No Pain, Big Gain
No Pain, Big Gain
Kate Yandell | May 22, 2014
Eliminating a pain receptor makes mice live longer and keeps their metabolisms young.
Pain and Progress
Pain and Progress
Kerry Grens | Feb 1, 2014
Is it possible to make a nonaddictive opioid painkiller?
Centipede Venom Tops Morphine
Centipede Venom Tops Morphine
Kerry Grens | Oct 1, 2013
The substance targets the same ion channel that's mutated in people who don't feel pain.
Natural Opioids Linked to Chronic Pain
Natural Opioids Linked to Chronic Pain
Jef Akst | Sep 19, 2013
The body’s own pain-quelling system may be at the root of chronic pain and symptoms of opioid withdrawal, according to a new study in mice.
From Toxins to Therapeutics
From Toxins to Therapeutics
Dan Cossins | Mar 19, 2013
Researchers are finding new drugs for chronic pain and autoimmune diseases by modifying animal venom-derived molecules that target the nervous and immune systems.
Pain-Killing Transplants
Ed Yong | May 23, 2012
Neurons injected into mice help treat chronic pain at its roots, rather than simply alleviating its symptoms.
Metabolites Involved in Chronic Pain
Jeffrey M. Perkel | Jan 22, 2012
Untargeted metabolic profiling implicates a new suite of metabolites that may be involved in nerve damage-induced pain.