More Cancer Mutations, Better Immunotherapy Outcomes
More Cancer Mutations, Better Immunotherapy Outcomes
Immune checkpoint inhibitors are generally most effective against tumors with more genetic mutations, according to a new study, although the relationship isn’t true for all cancers.
More Cancer Mutations, Better Immunotherapy Outcomes
More Cancer Mutations, Better Immunotherapy Outcomes

Immune checkpoint inhibitors are generally most effective against tumors with more genetic mutations, according to a new study, although the relationship isn’t true for all cancers.

Immune checkpoint inhibitors are generally most effective against tumors with more genetic mutations, according to a new study, although the relationship isn’t true for all cancers.

citizen science, genetics & genomics, cell & molecular biology
Stem Cell–Derived Neurons from People with Autism Grow Differently
Stem Cell–Derived Neurons from People with Autism Grow Differently
Jef Akst | Jan 11, 2019
Changes in gene expression also hint at how the brains of people with ASD develop differently from those of other people.
Exosomes Linked to Cancer Spread from Chemoresistant Tumors in Mice
Exosomes Linked to Cancer Spread from Chemoresistant Tumors in Mice
Carolyn Wilke | Jan 10, 2019
The vesicles promote metastasis after chemotherapy, but the authors say the results shouldn’t alarm patients and may point to ways to improve treatments.
Eli Lilly Will Buy Loxo Oncology for $8 BillionEli Lilly Will Buy Loxo Oncology for $8 Billion
Eli Lilly Will Buy Loxo Oncology for $8 Billion
Ashley Yeager | Jan 8, 2019
Loxo focuses on cancer treatments based on tumor genetics, which will contribute to Lilly’s push in the cancer drug space.
AI App Identifies Rare Genetic Disorders from Photos of Patients’ Faces
AI App Identifies Rare Genetic Disorders from Photos of Patients’ Faces
Catherine Offord | Jan 8, 2019
Deep-learning algorithms could help doctors narrow in on the causes of certain medical conditions, say researchers.
Babies’ Genomes Identify Risks Overlooked by Newborn Screens
Babies’ Genomes Identify Risks Overlooked by Newborn Screens
Abby Olena | Jan 3, 2019
A trial called BabySeq, in which researchers performed genomic sequencing on 159 newborns, identified children susceptible to diseases that regular screening doesn’t look for.
Infographic: How Cities Influence Evolution
Infographic: How Cities Influence Evolution
Catherine Offord | Jan 1, 2019
Urban environments are driving genetic changes in resident species through multiple mechanisms, from establishing gene flow barriers to exerting novel selection pressures.
Researchers Aim to Reestablish an Ancient Fish in an Ohio River
Researchers Aim to Reestablish an Ancient Fish in an Ohio River
Shawna Williams | Jan 1, 2019
The sturgeon restoration study’s outcome won’t be known for decades.
The Open Data Explosion
The Open Data Explosion
Viviane Callier | Jan 1, 2019
Scientists are working to maximize the benefits and minimize the costs of sharing.
Researchers Engineer Epigenome Editors to Study How Gene Expression Affects Disease
Researchers Engineer Epigenome Editors to Study How Gene Expression Affects Disease
Ashley Yeager | Jan 1, 2019
Using CRISPR and other tools, scientists are modifying DNA methylation, histone marks, and other modifiers of gene expression to understand how they affect health and disease.