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Targeting Tregs Halts Cancer’s Immune Helpers
Ruth Williams | Apr 1, 2017
New monoclonal antibodies kill both cancer-promoting immunosuppressive cells and tumor cells in culture.
Infographic: Antibody Cancer Therapy
Ruth Williams | Mar 31, 2017
An experimental technique removes T cells that aid in vitro tumor growth.
Infographic: Targeting Cancer Antigens
Stephen P. Schoenberger and Ezra Cohen | Mar 31, 2017
Neoantigens may serve as valuable targets for new immunotherapies.
Anti-Flavivirus Antibodies Enhance Zika Infection in Mice
Anna Azvolinsky | Mar 30, 2017
Researchers report evidence of antibody-dependent enhancement in a Zika-infected, immunocompromised mouse model.
Experimental MERS Treatments Target Host Cell Receptor
Ashley Yeager | Mar 30, 2017
Researchers are searching for ways to prevent the coronavirus from attaching to DPP-4 receptors, blocking it from invading and replicating within host cells.
Unique Antibodies Open Path Toward New HIV Vaccines
Amanda B. Keener | Jan 27, 2017
A family of broadly neutralizing antibodies from a chronically infected donor provides a schematic for designing vaccines and treatments that target multiple strains of the virus.
Mouse Immunology Paper Retracted
Jef Akst | Dec 16, 2016
A finding of misconduct spurs the retraction of a
paper claiming to have identified a protein in mice that boosted immunity to both viruses and cancer.
Keeping CRISPR in Check
Anna Azvolinsky | Dec 14, 2016
In bacteriophage genomes, researchers find three anti-CRISPR proteins that naturally inhibit CRISPR-Cas9 in one bacterial species and can do the same in human cells.
Naive T Cells Find Homes in Lymphoid Tissue
Karen Zusi | Dec 2, 2016
The human lymph nodes and spleen maintain unique, compartmentalized sets of naive T cells well into old age.
Low Social Status May Weaken Immune System in Monkeys
Ben Andrew Henry | Nov 29, 2016
Life at the bottom of the pecking order ramps up inflammation, according to new research, an effect that appears to be reversible.