colorectal cancer

Cohesin mutations cause dysregulations in alternative splicing, contributing to tumor initiation and progression, a study finds. 

Most differences in gene expression among cells within a tumor are likely due to environment or noise, a study suggests. 

Disturbing circadian rhythms in organoids and mice increases intestinal tumor growth, findings that may explain a recent rise in colon cancer among young adults, the researchers behind the work say.

Selected Images of the Day from the-scientist.com

Colorectal tumor cells limit their DNA repair in response to a targeted therapy, giving them a greater chance to develop resistance to the drug.

Three-dimensional tissue cultures grown from cancer patients’ own tumors can predict responses to the drug irinotecan.

Some experts blame our modern, sugary diet, while others think that gut microbiome changes and sedentary lifestyles may play a role. Altogether, the causes are far from clear.

The Creighton University researcher discovered the genetic basis of hereditary breast-ovarian cancer syndrome.

Fly avatars bearing multiple genetic changes akin to those of a cancer patient lead to a tailor-made treatment that has shrunk the patient’s tumors.

Organoids grown from a mouse’s colon will be used to screen drugs for colorectal cancer.

The awards for comical but practical scientific discovery also include cannibalism and self-colonoscopy.

The test can pick up several types of cancer, including pancreatic and ovarian, years before symptoms appear.

Researchers did not observe the same link between a bacterium and human colon cancer that prior investigators had reported.

The new diagnostic works by identifying cancer-associated proteins and DNA in patient blood.