First Successful Gene Drive in Mammals
First Successful Gene Drive in Mammals
Researchers use a CRISPR-Cas9 strategy to expand a desired trait from 50 percent of mouse pups to about 72 percent.
First Successful Gene Drive in Mammals
First Successful Gene Drive in Mammals

Researchers use a CRISPR-Cas9 strategy to expand a desired trait from 50 percent of mouse pups to about 72 percent.

Researchers use a CRISPR-Cas9 strategy to expand a desired trait from 50 percent of mouse pups to about 72 percent.

CRISPR/Cas
First Successful Gene Drive in Mammals
First Successful Gene Drive in Mammals
Abby Olena | Jan 23, 2019
Researchers use a CRISPR-Cas9 strategy to expand a desired trait from 50 percent of mouse pups to about 72 percent.
Taming the Transposon Hordes
Taming the Transposon Hordes
Ruth Williams | Jan 1, 2019
Researchers repurpose the CRISPR machinery to turn whole classes of transposable elements on or off.
Photos of the Year
Photos of the Year
Carolyn Wilke | Dec 21, 2018
From 500-million-year-old fat to a newly discovered virus, here are some stunners from The Scientist in 2018.
Claim of First Gene-Edited Babies Triggers Investigation
Claim of First Gene-Edited Babies Triggers Investigation
Catherine Offord | Nov 26, 2018
He Jiankui says he has successfully used CRISPR-Cas9 to tweak the genes of twins born earlier this month. Some independent experts are dubious.
CRISPR Editing Heads Off Disease in Mouse LiversCRISPR Editing Heads Off Disease in Mouse Livers
CRISPR Editing Heads Off Disease in Mouse Livers
Shawna Williams | Oct 9, 2018
Separate proof-of-concept studies report success against two inherited diseases.
New Technique Limits CRISPR-Cas9 Off-Target Mutations
New Technique Limits CRISPR-Cas9 Off-Target Mutations
Abby Olena | Sep 12, 2018
A mouse study details a method called VIVO that predicts the accuracy of any guide RNA.
Federal Court Sides with Broad in CRISPR Patent Dispute
Federal Court Sides with Broad in CRISPR Patent Dispute
Jef Akst | Sep 10, 2018
The higher court’s decision to uphold the ruling of the Patent Trial and Appeal Board essentially ends the intellectual property battle in the US.
US Companies Launch CRISPR Clinical Trial
US Companies Launch CRISPR Clinical Trial
Catherine Offord | Sep 3, 2018
The Germany-based study will test an ex vivo genome-editing therapy for the inherited blood disorder β-thalassemia.
Electric Shock Allows for CRISPR Gene Editing Without a Viral Vector
Electric Shock Allows for CRISPR Gene Editing Without a Viral Vector
Ashley Yeager | Jul 12, 2018
Brief electroporation appears to make T cells more receptive to new genetic material, which could speed the development of immunotherapies.
CRISPR Gene Drive Used to Alter Mouse Coat Color
CRISPR Gene Drive Used to Alter Mouse Coat Color
Shawna Williams | Jul 9, 2018
It’s the first demonstration of the technology in mammals.