A series of brain scans on a black background
How Scientists Are Tackling Brain Imaging’s Replication Problem
Researchers who spoke with Spectrum say that while brain imaging tools have their limitations, they still hold promise in helping to unlock the brain’s secrets. 
How Scientists Are Tackling Brain Imaging’s Replication Problem
How Scientists Are Tackling Brain Imaging’s Replication Problem

Researchers who spoke with Spectrum say that while brain imaging tools have their limitations, they still hold promise in helping to unlock the brain’s secrets. 

Researchers who spoke with Spectrum say that while brain imaging tools have their limitations, they still hold promise in helping to unlock the brain’s secrets. 

DEET, neuroscience
illustration of a scientist carrying a test tube and leaping over a large coronavirus while carrying two children on her back
Pandemic Pressures May Drive Young Scientists Away from Autism Research
Grace Huckins | Jun 18, 2021
For researchers who work with study participants in person, lockdowns made it impossible to obtain fresh data, a survey finds.
Two fingers grasp a vitamin D capsule
Vitamin D Deficiency Drives Opioid Addiction in Mice
Amanda Heidt | Jun 16, 2021
Mice with low vitamin D had exaggerated craving for opioids and felt the drugs’ effects more strongly—results supported in part by human medical records—suggesting that supplements should be explored as treatments for opioid use disorders.
Two oligodendrocyte progenitor cells are being generated from adult stem cells nestled on the surface of brain ventricle
Scientists Discover “Gorditas” and Other Novel Brain Cell Types
Amanda Heidt | Jun 10, 2021
A pool of neural stem cells that ordinarily lies dormant in the brains of adult mice spawns two types of never-before-documented glial cells when artificially reactivated, potentially pointing to a novel mechanism of brain plasticity.
Updated
blue and white sign for the entrance to the FDA that says U.S. Department of Health and Human Services Food and Drug Administration
Biogen’s Alzheimer’s Drug Gets FDA Approval, Mixed Reviews
Kerry Grens | Jun 7, 2021
A lackluster performance in clinical trials of the monoclonal antibody aducanumab has left some experts unconvinced of its benefit.
panel depicting mossy fiber synapses and glutamate signaling dynamics
Infographic: Reverse Signaling Between Neurons
Christie Wilcox | Jun 4, 2021
So-called mossy fiber synapses in the hippocampus can meter the amount of neurotransmitter they receive by sending glutamate against the usual direction of synaptic flow.
artistic representation of a neuron synapse with light and dark dots passing between two axons
Hippocampal Cell Communication Is Bidirectional: Study
Christie Wilcox | Jun 4, 2021
In an unexpected twist in neuroscience dogma, the cells on the receiving end of neurotransmission appear to be able to release glutamate to regulate the transmitting cell’s activity.
illustration of brain cells in blue with amyloid plaques in orange and pink immune cells
Excerpt from The Memory Thief
Lauren Aguirre | Jun 1, 2021
Author Lauren Aguirre finds reasons for optimism in the fight against Alzheimer’s disease.
illustration of a neuron connected to other neurons
Opinion: The Overlooked Power of Inhibitory Neurons
Lauren Aguirre | Jun 1, 2021
Understanding how the brain coordinates electrical activity could be key to developing more-effective treatments for a variety of brain disorders.
Broken Heart Syndrome Linked to the Brain
Amanda Heidt | Jun 1, 2021
A chronically stressed amygdala can prime the heart to overreact to acute stress events, a new study shows.
Contributors
The Scientist Staff | Jun 1, 2021
Meet some of the people featured in the June 2021 issue of The Scientist.
a drawing of black goggles receiving a beam of light than is then transmitted to an eyeball. from the retina there is a zoom-in of blue and purple cells and purple viruses
Blind Patient Recovers Partial Vision with Optogenetics
Alejandra Manjarrez | May 24, 2021
After receiving an intraocular injection of the gene for a light-sensitive protein, a 58-year-old man diagnosed with the neurodegenerative eye disease retinitis pigmentosa was able to locate objects on a table using engineered goggles.
Hippocampal neurons are labeled in blue and purple on a black background
New Role for Leptin: Promoting Synapse Formation in Rat Neurons
Abby Olena | May 20, 2021
The hormone, which is well known for regulating appetite, appears to influence neuronal development—a finding that could shed light on disorders such as autism that involve dysfunctional synapse formation.
an illustration of a man with electrodes in his brain thinking about writing the word "hello," and the word appearing on a computer screen
Brain-Computer Interface User Types 90 Characters Per Minute with Mind
Shawna Williams | May 13, 2021
The experimental system, developed and tested in just one patient so far, relies on brain signals associated with handwriting to achieve the fastest communication yet seen with BCI.