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A mouse stands behind a toy table with two pieces of food on it.
A Protein-Sensing Molecular Switch Alters Facial Features
The mTORC1 signaling pathway senses nutritional information and influences craniofacial development in mice.
A Protein-Sensing Molecular Switch Alters Facial Features
A Protein-Sensing Molecular Switch Alters Facial Features

The mTORC1 signaling pathway senses nutritional information and influences craniofacial development in mice.

The mTORC1 signaling pathway senses nutritional information and influences craniofacial development in mice.

developmental biology

A developing embryo with DNA labeled blue, cell boundaries labeled pink, and certain cells fluorescing green.
The First Two Cells in a Human Embryo Contribute Disproportionately to Fetal Development
Shelby Bradford, PhD | May 13, 2024 | 4 min read
A research team showed that, contrary to current models, one early embryonic cell dominates lineages that will become the fetus.
Red cells encased in cyan webbing. 
Fetal Organoids Generated From Human Amniotic Fluid
Danielle Gerhard, PhD | May 3, 2024 | 6 min read
A minimally invasive strategy for creating fetal organoids could facilitate precision medicine in the womb.
Key Strategies for Better Stem Cell Workflows
Solutions for Optimizing Stem Cell Therapy Development
Sartorius | 1 min read
Discover how process knowledge is integral to stem cell workflow improvement and optimization.
An image of cells with the center stained green and some cells stained magenta over a black background.
Growing Milk-Secreting Mammary Organoids
Sneha Khedkar | Mar 29, 2024 | 3 min read
Mammary organoids derived from mouse embryonic stem cells could offer clues into mammary gland developmental origins and help researchers study breast cancer.
Fluorescent microscopy image of an embryo model representing four tissue layers of this developmental stage. Cyan-labeled cells are clustered at the top of an ovoid structure, underneath them are yellow-labeled cells and under them red-labeled cells, and surrounding all three layers are white labeled cells.
The First Human Embryo Model From Embryonic Stem Cells
Shelby Bradford, PhD | Mar 1, 2024 | 2 min read
Jacob Hanna developed a method for replicating embryogenesis outside of the uterus to understand the underlying mechanisms.
A Brief History of Stem Cells
Scientific Breakthroughs with Stem Cells
Nele Haelterman, PhD | 1 min read
Discover the various ways scientists bolster stem cells to understand and cure disease.
A mouse embryo in which the head, spine, and limb buds are visible.
Illuminating Craniofacial Development
Hannah Thomasy, PhD | Jan 1, 2024 | 2 min read
Paul Trainor delves into the genetic and environmental factors that shape the head and face.
On the left is a normally developing mouse embryo, on the right is a slightly larger mouse embryo that also contains horse cells that glow green.
Chimera research opens new doors to understanding and treating disease
Hannah Thomasy, PhD, Drug Discovery News | Aug 9, 2023 | 10 min read
Animals with human cells could provide donor organs or help us understand neuropsychiatric disorders.
Harnessing Stem Cells to Treat Disease
Harnessing Stem Cells to Treat Disease
The Scientist | 1 min read
In this webinar, Kim Vanuytsel and Ryan Flannigan will discuss cutting-edge technologies for improving stem cell-based therapies.
Chromosome with gold band
Immunity Genes May Play a Role in Down Syndrome
Kamal Nahas, PhD | Jul 6, 2023 | 4 min read
Extra copies of four interferon receptor genes found on human chromosome 21 trigger developmental changes in a mouse model of Down syndrome.
Image of in vitro fertilization
Should the scientific community abandon the 14-day rule for research on human embryos?
Ida Emilie Steinmark, PhD | Jul 5, 2023 | 2 min read
Research on human embryos is usually limited to the first 14 days of development, but as scientific capabilities improve, some argue that it is time to go further.
Sample Preparation with Single Cell Multiomics: Simultaneous Epigenomic and Transcriptomic Profiling from the Same Cell
The Scientist | 1 min read
In this webinar brought to you by 10x Genomics, experts will discuss how to successfully prepare nuclei suspensions for Single Cell Multiome ATAC + Gene Expression experiments.
A fluorescence microscopy image of placenta tissue made up of cells dyed blue, purple, pink and green on a black background.
The Cellular Intricacies of the Human Placenta
Ida Emilie Steinmark, PhD | Jul 5, 2023 | 2 min read
Rare samples saved 35 years ago helped researchers map gene expression and cell differentiation in first trimester placentas.
Photo of Claudia Gerri
Claudia Gerri Studies the Mysteries of the Placenta
Katherine Irving | Feb 1, 2023 | 3 min read
At the Max Planck Institute of Molecular Cell Biology and Genetics, the developmental biologist is probing the maternal-fetal interface across mammalian species.
Getting Started with Single Cell Multiomics: Simultaneous Epigenomic and Transcriptomic Profiling from the Same Cell
The Scientist | 1 min read
In this webinar brought to you by 10x Genomics, experts will discuss tips for running Chromium Single Cell Multiome ATAC + Gene Expression experiments in your lab.
a human neuron illuminated in bright green on a black background.
Mitochondrial Metabolism Dictates Neurons’ Growth Rate
Katherine Irving | Jan 30, 2023 | 4 min read
Altering the rate of respiration in mitochondria changes how fast neurons grow, making mouse neurons grow more like human ones and vice versa, a study finds.
Collage of faces
Remembering Those We Lost in 2022
Lisa Winter | Dec 26, 2022 | 5 min read
A look at some noteworthy scientists who died this year, leaving behind a legacy of research excellence.
A colored microscopy image showing cells that are dying in yellow and healthy cells in blue 
Sweet Taste Receptors Regulate Proteins in Developing Fruit Flies
Tess Joosse | Nov 14, 2022 | 2 min read
An unexpected find shows that sweet-sensing receptors also help epithelial cells in Drosophila larvae stay alive amid proteotoxic stress.
Embryonic gecko hand
Science Snapshot: Show of Hands
Lisa Winter | Oct 28, 2022 | 1 min read
This image took the top prize at the 2022 Nikon Small World Photomicrography Competition.
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