artistic rendering of CRISPR/Cas9
Ten Years of CRISPR
This month marks ten years since CRISPR-Cas9 was repurposed as a gene editing system, so we’re looking back at what has been accomplished in a decade of CRISPR editing.
Ten Years of CRISPR
Ten Years of CRISPR

This month marks ten years since CRISPR-Cas9 was repurposed as a gene editing system, so we’re looking back at what has been accomplished in a decade of CRISPR editing.

This month marks ten years since CRISPR-Cas9 was repurposed as a gene editing system, so we’re looking back at what has been accomplished in a decade of CRISPR editing.

diagnostics
Tumor microbiome composite
Could Cancer’s Microbiome Help Diagnose and Treat the Disease?
Jef Akst | Mar 14, 2022
A growing appreciation of the bacterial assemblages that live within tumors has researchers striving to understand and capitalize on their role.
Illustration showing microbial signatures of cancer in the body
Infographic: Putting Cancer’s Unique Microbiomes to Use
Jef Akst | Mar 14, 2022
From diagnosis to tracking treatment responses, bacteria and other microbes in the blood, gut, and tumors of cancer patients may provide helpful hints for improving their care.
Discover How to Design Sensitive Nucleic Acid Lateral Flow Assays
Go with the Flow: Adapting Lateral Flow Assays for Nucleic Acid Detection
The Scientist Creative Services Team and nanoComposix
Scientists incorporate sensitive nanoparticles to rapidly detect DNA and RNA.
Rapid antigen tests for SARS-CoV-2
Are Rapid Tests Worse at Detecting Omicron—and Does It Matter?
Catherine Offord | Jan 14, 2022
Anecdotal reports and results from small studies on the diagnostics’ accuracy have prompted questions about the devices’ usage with the new variant, but researchers say more data are needed and emphasize the continued importance of SARS-CoV-2 testing.
A Theranos sign outside the company's headquarters
Theranos Founder Elizabeth Holmes Convicted of Fraud
Amanda Heidt | Jan 4, 2022
After a week of deliberation, a jury returned a guilty verdict on four charges related to wire fraud, each of which carries a maximum sentence of up to 20 years in prison.
Improve qPCR Efficiency and Reproducibility
The Components of Effective qPCR
The Scientist Creative Services Team and Bio-Rad Laboratories
Putting the pieces together for molecular diagnostics and infectious disease research
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist Staff | Dec 1, 2021
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
orange and blue cell image
Woman’s Body Appears to Rid Itself of HIV
Chloe Tenn | Nov 18, 2021
Researchers report what appears to be the second case of a person’s immune system clearing the virus on its own.
gold nanoshells
Getting More Lateral Flow Test Sensitivity with Nanoshell Probes
The Scientist Creative Services Team and nanoComposix
Silica-gold nanoshells highlight how good probe design can boost assay performance.
photograph of miSHERLOCk device against a white background
A Self-Contained COVID-19 Test with 3-D Printed Parts
Annie Melchor | Aug 11, 2021
The makers of the CRISPR-based testing platform, called miSHERLOCK, say it could enable people at home or physicians in resource-limited environments to detect SARS-CoV-2—and eventually, other pathogens.
Sodas, Lemon Juice Cause False Positives in Rapid COVID-19 Tests
Christie Wilcox | Jul 12, 2021
Lateral flow tests for COVID-19 can be very accurate and specific when used as directed, but introducing acidic fluids can cause the tests’ detecting antibodies to clump, which may read as a positive result.
800x800
A 3-D Tumor Microenvironment for Personalized Immunotherapy
Roni Dengler, PhD
A new platform enables screening a wide range of combination anticancer therapeutics in a matter of days, which may translate to personalized therapeutic regimens for patients in less time.
photograph of a woman wearing a face mask embedded with SARS-CoV-2 sensors
Researchers Create Pathogen-Sensing Face Mask
Annie Melchor | Jul 5, 2021
The masks contain freeze-dried, cell-free biosensors, enabling them to detect pathogens including SARS-CoV-2.
The Researchers Who Pivoted to COVID-19: One Year On
Shawna Williams | Jul 1, 2021
The Scientist checks in on scientists who switched gears to combat the pandemic.
800x560-misherlock-0916
A New COVID-19 Spit Test Is as Easy as 1-2-3
Roni Dengler, PhD
A device smaller than two stacked decks of cards can reliably detect and discriminate between SARS-CoV-2 variants in spit in less than an hour with results that glow.
a close up photo of a black dog nose with blond and white whiskers
Dogs: The New COVID-19 Rapid Test
Kerry Grens | May 24, 2021
Two studies this month point to pooches’ quick detection of SARS-CoV-2 on material that touched the skin of infected participants, although the pups’ accuracy does not match that of RT-PCR.
clear blood draw tubes with peach-colored caps and white labels with a red banner that has a DNA double helix icon and the word text. inside the tubes is a conceptual drawing of a DNA double helix in white
FDA-Led Consortium Details Improvements Needed in Liquid Biopsies
Marcus A. Banks | May 19, 2021
In the largest effort to date to standardize performance metrics of the cancer diagnostic across products, researchers say the products can likely detect advanced tumors reliably, but early-stage malignancies would remain a challenge.
Glucometers Detect SARS-CoV-2 Infection Within an Hour
Roni Dengler, PhD
Glucometers are easy-to-use, cheap, and highly scalable. And they are 100 percent accurate at detecting SARS-CoV-2.
Helen Murray Free smiling at the camera, wearing a red shirt and black jacket with red trim.
Diabetes Testing Pioneer Helen Free Dies at 98
Lisa Winter | May 5, 2021
Free’s dip-and-read urinalysis allowed diabetics to monitor glucose levels at home, rather than at a hospital.