Thousands of <em>BRCA1</em> Genetic Variants Functionally Characterized
Thousands of BRCA1 Genetic Variants Functionally Characterized
The researchers catalogued 3,893 variants of the gene implicated in cancer using CRISPR.
Thousands of BRCA1 Genetic Variants Functionally Characterized
Thousands of BRCA1 Genetic Variants Functionally Characterized

The researchers catalogued 3,893 variants of the gene implicated in cancer using CRISPR.

The researchers catalogued 3,893 variants of the gene implicated in cancer using CRISPR.

Drosophila, culture, genetics & genomics, immunology
As Bees Specialize, So Does Their DNA Packaging
As Bees Specialize, So Does Their DNA Packaging
Shawna Williams | Sep 11, 2018
A study of chemical tags on histone proteins hints at how the same genome can yield very different animals.
Anti-CRISPR Proteins Found that Block Cas12a Nuclease
Anti-CRISPR Proteins Found that Block Cas12a Nuclease
Ashley Yeager | Sep 6, 2018
Using bioinformatics, two teams of scientists identified inhibitory proteins for Cas9’s relative.
AACR Apologizes for Delays in Retracting Papers
AACR Apologizes for Delays in Retracting Papers
Catherine Offord | Sep 5, 2018
Nine of the most recent retractions from AACR journals are for papers coauthored by embattled cancer researcher Bharat Aggarwal.
RNA Detection Tool Debate Flares Up at ACS Meeting &nbsp;
RNA Detection Tool Debate Flares Up at ACS Meeting  
Katarina Zimmer | Sep 5, 2018
Researchers have flagged several issues with so-called SmartFlares over the years, and it’s still unclear why they don’t appear to work under certain circumstances.
Early Results of First In Vivo Gene-Editing Trial Encouraging
Early Results of First In Vivo Gene-Editing Trial Encouraging
Kerry Grens | Sep 5, 2018
Two patients who received Sangamo’s zinc finger–based treatment for Hunter syndrome have lower biomarkers of the condition, but no signs of new enzyme production.
Image of the Day: Ocean Wonder
Image of the Day: Ocean Wonder
Sukanya Charuchandra | Sep 4, 2018
Molecules similar to those produced by sea anemones are neuroprotective in a mouse cell model of Alzheimer’s disease.
Wellcome Sanger Institute Leaders Accused of Bullying
Wellcome Sanger Institute Leaders Accused of Bullying
Jef Akst | Sep 4, 2018
Several members of senior management at the prestigious UK research center face claims of sexism and mistreatment of staff.
US Companies Launch CRISPR Clinical Trial
US Companies Launch CRISPR Clinical Trial
Catherine Offord | Sep 3, 2018
The Germany-based study will test an ex vivo genome-editing therapy for the inherited blood disorder β-thalassemia.
Ten-Minute Sabbatical
Ten-Minute Sabbatical
The Scientist Staff | Sep 1, 2018
Take a break from the bench to puzzle and peruse.