Arthur Riggs smiles for the camera
Geneticist Arthur Riggs Dies at 82
Lisa Winter | Apr 14, 2022
His research paved the way for the development of synthetic insulin to treat diabetes.
Ramified cells in a lilac background
Could Vitamin Supplementation Help Alzheimer’s Patients?
Alejandra Manjarrez | Apr 11, 2022
Niacin, a form of vitamin B3 used to treat cardiovascular disease, helps immune cells in the brain fight neurodegenerative diseases such as Alzheimer’s in mice models, according to recent studies. Researchers hope that human clinical trials will swiftly follow.
Learn about universal documentation for easy compliance testing
Simplify Laboratory Compliance with Universal Documentation
The Scientist Creative Services Team, PerkinElmer | Apr 21, 2022
Universal electronic documentation takes care of instrument compliance testing, allowing researchers to get back to the bench.
Magnifying glass in front of a stack of files of papers
PLOS ONE Pulls Five Papers Tied to Alzheimer’s Drug Controversy
Jef Akst | Mar 31, 2022
The retracted studies were coauthored by a scientist who worked on an Alzheimer’s therapy in development by Cassava Sciences, a company reportedly under investigation for providing falsified data to the FDA.
Four white, circular pills balance on their side in front of a pink background.
Metformin Prescriptions Linked to Sons’ Birth Defects
Dan Robitzski | Mar 29, 2022
A new cohort study finds that boys whose fathers took the type 2 diabetes drug metformin three months before their conception were more likely to have a birth defect.
Human DNA stock photo
Setting Better Traps for PARP Inhibitors
The Scientist Creative Services Team, BPS Bioscience | Apr 19, 2022
An innovative assay permits researchers to screen for small molecule PARP inhibitors that trap the enzyme on DNA and selectively execute cancer cells.
Image of brain cells showing pyramidal neurons in green, astrocytes in red, and microglia in blue
Replacing Microglia Treats Neurodegenerative Disease in Mice
Shawna Williams | Mar 17, 2022
Researchers find a way to wipe out the brain’s immune cell corps and send in new and improved versions.
Zebrafish with fluorescent nervous system in green.
Oust the Mouse: A Plan to Reduce Mammal Use in Drug Development
Natalia Mesa | Mar 15, 2022
The Scientist spoke to Mount Desert Island Biological Laboratory’s Jim Strickland about the institute’s new MDI Bioscience initiative to perform more drug testing and development in nonmammalian models.
Don Ingber discusses how organ-on-a-chip technology helps identify, study, and combat viral variants that could cause the next pandemic.
The Scientist Speaks - Preventing the Next Pandemic with Organ Chips
Nele Haelterman, PhD | Mar 30, 2022
Don Ingber discusses how organ-on-a-chip technology helps identify, study, and combat viral variants that could cause the next pandemic.
An orange CRISPR Cas 9 enzyme cutting DNA
CRISPR-Based Treatment Successfully Lowers Toxic Protein Levels
Natalia Mesa | Mar 2, 2022
A first-of-its-kind gene therapy dramatically reduced misfolded protein levels in some clinical trial participants for up to six months and reduced levels in all participants for up to a year.
A masked doctor in a white coat and blue gloves administers a vaccine into the arm of a masked child.
Pfizer Vaccine Less Protective for Younger Kids: Preprint
Dan Robitzski | Feb 28, 2022
The vaccine’s effectiveness in children ages 5 to 11 rapidly declined over the course of a month, according to new research that looked at the health outcomes of hundreds of thousands of children in New York during the Omicron surge.
Recombinant proteins have a wide range of research and clinical applications.
Introducing Custom Recombinant Expression Services at the Cutting Edge of Biomolecular Engineering
The Scientist Creative Services Team, Sino Biological | Mar 24, 2022
A turnkey CRO service platform for recombinant protein and antibody expression and production
Doctor holding stethoscope in front of European Union flag
New EU Protocol Aims to Improve Clinical Trial Transparency
Sophie Fessl | Feb 16, 2022
A new regulation and registry covering investigational medicinal products mandates reporting and supports multinational trials.
hundred dollar bills with stethoscope on top
Most Medical Papers Didn’t Disclose Industry Payments: Preprint
Natalia Mesa | Jan 24, 2022
Authors of papers published in JAMA and NEJM received millions in undisclosed payments in 2017, an analysis finds.
Discover how to effectively purify biomolecules with chromatography
Streamlined Purification Workflows for Biomolecule Production
The Scientist Creative Services Team, Bio-Rad Laboratories | Mar 23, 2022
Researchers optimize chromatography-based workflows to purify biomolecules at scale.
knitted pink heart with a mended hole
CAR T Cells Mend Broken Mouse Hearts
Sophie Fessl | Jan 6, 2022
Specialized immune cells generated in vivo reduce cardiac scar tissue in mice, a new study shows.
headshot man
Ophthamologist Alan Scott Dies at Age 89
Chloe Tenn | Dec 29, 2021
The Smith-Kettlewell Eye Research Institute scientist developed Botox for medicinal use.
Clear and Easy Flowing: Analyzing Antibody Self-Interactions
Strategies for the Rapid Assessment of Antibody Self-Interactions and Improved Formulations Development
The Scientist Creative Services Team, Sartorius | Feb 2, 2022
Martin Domnowski explains how sequence and formulation affect antibody self-interaction properties, and how researchers detect these interactions in low concentration samples.
Several silver foil pill packs with white pills
FDA Authorizes Pfizer’s Paxlovid, First Oral Therapy for COVID-19
Jef Akst | Dec 23, 2021
Given within three days of symptom onset, the pill combination was nearly 90 percent effective at preventing high-risk patients from developing severe illness in a clinical study.
Cover image of "Venomous" by Christie Wilcox, along with a headshot of the author and introduction title
Book Club Discussion of Venomous by Christie Wilcox
The Scientist Social Club | Dec 10, 2021
The Scientist Social Club sat down with the author.