drug development

His research paved the way for the development of synthetic insulin to treat diabetes.

Niacin, a form of vitamin B3 used to treat cardiovascular disease, helps immune cells in the brain fight neurodegenerative diseases such as Alzheimer’s in mice models, according to recent studies. Researchers hope that human clinical trials will swiftly follow.

The retracted studies were coauthored by a scientist who worked on an Alzheimer’s therapy in development by Cassava Sciences, a company reportedly under investigation for providing falsified data to the FDA.

A new cohort study finds that boys whose fathers took the type 2 diabetes drug metformin three months before their conception were more likely to have a birth defect.

Researchers find a way to wipe out the brain’s immune cell corps and send in new and improved versions.

The Scientist spoke to Mount Desert Island Biological Laboratory’s Jim Strickland about the institute’s new MDI Bioscience initiative to perform more drug testing and development in nonmammalian models.

A first-of-its-kind gene therapy dramatically reduced misfolded protein levels in some clinical trial participants for up to six months and reduced levels in all participants for up to a year.

The vaccine’s effectiveness in children ages 5 to 11 rapidly declined over the course of a month, according to new research that looked at the health outcomes of hundreds of thousands of children in New York during the Omicron surge.

A new regulation and registry covering investigational medicinal products mandates reporting and supports multinational trials.

Authors of papers published in JAMA and NEJM received millions in undisclosed payments in 2017, an analysis finds.

Specialized immune cells generated in vivo reduce cardiac scar tissue in mice, a new study shows.

The Smith-Kettlewell Eye Research Institute scientist developed Botox for medicinal use.

Given within three days of symptom onset, the pill combination was nearly 90 percent effective at preventing high-risk patients from developing severe illness in a clinical study.

The Scientist Social Club sat down with the author.