Artist’s rendition of neural connections, with inactive neurons in the background
Ketamine Flips a “Switch” in Mice’s Brain Circuitry: Study
Andy Carstens | Dec 9, 2022 | 6 min read
After injecting moderate doses of the dissociative anesthetic into the animals, previously “awake” brain cells go dark, and those that had been dormant suddenly light up.
An excited-looking toddler crawls towards toys while her mother watches on.
Doctors Treat a Rare Genetic Condition Before Patient Is Born
Dan Robitzski | Nov 10, 2022 | 2 min read
Thanks to continued weekly medications, a 16-month-old girl shows no symptoms of a severe genetic disease that typically kills children before they turn two.
Learn about rapid cell screening for antibody therapeutic discovery
The Future of Antibody Discovery for Biotherapeutics
Sartorius | 1 min read
Modern screening methods help usher in a new age of antibody therapeutics. 
magic mushrooms on a while background
Psilocybin Relieves Some Treatment-Resistant Depression Cases: Trial
Shawna Williams | Nov 3, 2022 | 2 min read
The research has caveats, including side effects and a lack of durability in the benefits of a single dose.
Circular clusters of <em>Staphylococcus aureus</em> drift on a blue background.
Retching Mice Reveal the Brain Circuit Behind Vomiting
Katherine Irving | Nov 2, 2022 | 2 min read
The discovery could one day lead to the development of better antinausea medications.
Learn how AI Advances Science&nbsp;
Breaking Through Big Data Bottlenecks
Tecan | 1 min read
Discover how machine learning helps scientists accelerate their research.  
A vial labeled &ldquo;RSV vaccine&rdquo; on a reflective surface next to a syringe.
After Decades of Delays, RSV Vaccines Show Promise in Early Data 
Dan Robitzski | Nov 1, 2022 | 3 min read
Both Pfizer and GSK have shared preliminary data suggesting that their experimental vaccines can protect older adults and newborn infants from the virus.
A vet and technician take a sample from a dog for use in PetDx&rsquo;s OncoK9 test, which screens cell-free DNA for genomic alterations associated with cancer.
The Pet Health Industry Takes on Canine Cancer
Diana Kwon | Oct 17, 2022 | 9 min read
Advanced genomic tools have provided biotech companies new approaches to help our furry friends—but experts say several limitations remain.
Learn about establishing a Gene Therapy Manufacturing Strategy&nbsp;
Considerations for Gene Therapy Manufacturing Strategies
Thermo Fisher Scientific | 1 min read
Discover tips for setting up and optimizing adeno-associated virus production.
a person fumigates a red brick pathway to control mosquitoes in the fight against Dengue virus.
European Medicines Agency Recommends Approving Takeda’s Dengue Vaccine
Katherine Irving | Oct 14, 2022 | 2 min read
In clinical trials, the new inoculation demonstrated greater protection for children and people older than 45 than the existing dengue vaccine.
Man with blue shirt and tie smiling at camera.
Pharmacologist and Olympian David Bailey Dies at 77
Lisa Winter | Oct 7, 2022 | 3 min read
He was best known for his discovery that grapefruit juice makes some medications less effective or potentially dangerous.
Medical and medicine laboratory stock photo
The Importance of Growth Factor Quality in Organoid Cultures
The Scientist Creative Services Team and Sino Biological | 3 min read
Optimizing organoid growth using pure, highly active, and consistent growth factors.
A black and white photo of a woman in a plumed hat in a laboratory classroom with several men
Birth of The Pill, 1956–1960
Andy Carstens | Oct 3, 2022 | 2 min read
Researchers overseeing the clinical trial for the first FDA-approved oral contraceptive claimed the drug gave the Puerto Rican participants power over their family planning. Critics claimed the women were exploited.
Illustration of light blue neurons with white amyloid plaques accumulating on their axons.
New Alzheimer’s Drug Slows Cognitive Decline in Clinical Trial
Dan Robitzski | Sep 28, 2022 | 2 min read
The Biogen-developed treatment, called lecanemab, appears to have a more clear-cut effect on slowing the disease than the company’s previous Alzheimer’s drug, Aduhelm.
Discover the potential of AAV vectors for gene therapy delivery
From Concept to Cure: Using AAV in Gene Therapy
The Scientist Creative Services Team and Bio-Rad Laboratories | 1 min read
With the right tools and techniques, researchers develop safe and effective adeno-associated virus (AAV)-based gene therapies.
A germinal center inside a lymph node
Slow Vaccine Delivery May Maximize Immune Response
Alejandra Manjarrez, PhD | Sep 23, 2022 | 5 min read
A vaccine strategy involving formulation changes, an initial escalating dose, and a longer wait for booster immunization results in more-effective antibody production against HIV in rhesus monkeys, a study finds.
Histology of mouse lungs using purple and green staining on a white background. Left: a healthy lung. Right: a fibrotic lung.<br><br>
Immunotherapy Treats Fibrosis in Mice
Alejandra Manjarrez, PhD | Sep 15, 2022 | 4 min read
Researchers report that vaccination against proteins found on profibrotic cells reduced liver and lung fibrosis in laboratory rodents.
Discover how to effectively purify biomolecules with chromatography
Streamlined Purification Workflows for Biomolecule Production
Bio-Rad Laboratories | 1 min read
Researchers optimize chromatography-based workflows to purify biomolecules at scale.
illustration of blue cells with exosomes budding off of them and floating away
Nanoparticles Spur Mouse Immune System to Attack Cancer
Shafaq Zia | Sep 13, 2022 | 2 min read
A study finds that engineered exosomes are effective in mice, but their potential use in humans raises safety questions.  
woman smiling at camera
Renee Wegrzyn Tapped to Head ARPA-H
Andy Carstens | Sep 12, 2022 | 2 min read
As the new agency’s director, the DARPA veteran will spearhead a high-risk, high-reward approach to biomedical research.