Fluorescent microscopy image of two adult&nbsp;<em >C. elegans</em> and several offspring.
Automating In Vivo Screens and Challenging Dogma 
Deanna MacNeil, PhD | Jun 19, 2024 | 3 min read
Scientists built a microfluidic lab-on-a-chip device that accelerates compound screens and phenotype analyses in C. elegans models of reproductive aging.
Cuboidal DNA origami block containing parallel double helices (gray columns) decorated with tumor antigens (green proteins) and CpG adjuvants (yellow helices) on opposing faces.
Fighting Tumors with DNA Origami
Kamal Nahas, PhD | May 6, 2024 | 5 min read
Researchers bolster antitumor immune defenses using cancer vaccines made from DNA origami.
Preparing Samples for Single Cell Methods
Preparing Samples for Single Cell Methods
The Scientist Staff | 1 min read
Arpita Kulkarni will share tips and tricks for successful single cell RNA sequencing experiments.
An abstract illustration of a DNA helix and human lungs.
A New Delivery System Offers Hope for Cystic Fibrosis
Charlene Lancaster, PhD | May 1, 2024 | 4 min read
CRISPR-carrying lipid nanoparticles enabled researchers to correct a rare nonsense mutation in the lungs of a cystic fibrosis mouse model.
3D rendered RNA strand
MEGA CRISPR: Engineering Better Immunotherapies with RNA Editing
Deanna MacNeil, PhD | Apr 1, 2024 | 3 min read
Multi-targeted Cas13 screens help researchers avoid permanent DNA cuts and evade T cell exhaustion.
Spherical viruses with spiked membrane proteins on their surfaces surround larger suspended cancer cells.&nbsp;
Introduction to Oncolytic Virotherapy 
Amielle Moreno, PhD | 8 min read
Oncolytic virotherapy selectively attacks tumors and triggers both immediate and long-lasting immune responses. 
Top 10 Innovations 2024 logo
Enter Our 2024 Top 10 Innovations Contest
The Scientist | Apr 1, 2024 | 2 min read
Submit your new product for a chance at being selected for a coveted spot in The Scientist’s 2024 competition.
A scientist in the middle of the screen is in a lab coat in a laboratory on the left but is dressed in a suit giving a scientific presentation in a board room on the right.
Starting Up a New Endeavor
Shelby Bradford, PhD | Apr 1, 2024 | 2 min read
In his lab, Hashim Al-Hashimi investigated how RNA molecules move. Along the way, he founded a company.
A person typing at a laptop computer, with a digital overlay showing multiple files coming together to a central point.
A Unifying Data Informatics Approach for Multimodal Research
The Scientist and Sapio Sciences | 4 min read
As drug research becomes more interdisciplinary, data informatics needs to keep up and accommodate a diverse array of inputs and requirements. 
An illustration of purple-colored single domain antibodies floating in front of a black background.
Single Domain Antibodies: Small but Mighty Therapeutics
The Scientist | Mar 22, 2024 | 1 min read
Discover the benefits of VHH antibody-based therapies.
Infographic: Vaccinating Against Tumors
Shelby Bradford, PhD | Mar 15, 2024 | 1 min read
Cancer vaccines offer the opportunity to use the patient’s own immune system in the fight against tumors.
Teaching Old Drugs New Tricks
Teaching Old Drugs New Tricks
The Scientist Staff | 1 min read
Learn how scientists develop antibody drug conjugates as therapies for age-related diseases.   
A blue background with colorful illustrated viral particles
Delivering Prime Editors With Virus-like Particles
Deanna MacNeil, PhD | Mar 11, 2024 | 3 min read
An iterative engineering approach to improve prime editor delivery helped scientists correct genetic vision defects in mice.
Making Moves Toward Cell Therapy for Diabetes
Deanna MacNeil, PhD | Feb 20, 2024 | 3 min read
A step-by-step cell culture process may improve the quantity and quality of cell replacement therapies.
Industrial bioreactor with scientist in personal protective equipment
Introduction to Bioprocessing
Amielle Moreno, PhD | 7 min read
Bioprocessing employs the transformative power of biochemistry to drive sustainable production and pharmaceutical development.
Orange powder in a silver spoon, surrounded by orange pills on a blue background.
Turmeric Tackles Antimicrobial Resistance
Danielle Gerhard, PhD | Jan 1, 2024 | 2 min read
An active ingredient in turmeric interacts with light to resensitize pathogens to antibiotics.
Abstract illustration depicting coronavirus research concept.
Curiosity and Compassion Fuel Rare Disease Research
The Scientist Staff | Jan 1, 2024 | 1 min read
Lauren Drouin shares how personal connections and scientific curiosities drive her work on gene therapy viral vectors. 
Molecular illustration of CRISPR editing the DNA double helix
Prime Time Precision with CRISPR Technologies
The Scientist | 1 min read
Base editors and prime editors help researchers perform more precise in vivo and ex vivo translational research.
Infographic showing how a viral protein expression method links proteins and their coding instructions
Infographic: Phage Display Allows Rapid Screening of Millions of Peptides
Shelby Bradford, PhD | Dec 4, 2023 | 3 min read
A viral protein expression method links proteins and their coding instructions, enabling easier target identification for downstream analysis.
A Y-shaped pink, blue, and light green antibody is in focus on a background of blurred pink and purple color, with other antibodies out of focus in the background.
Phage Display: Finding the One in a Million
Shelby Bradford, PhD | Dec 4, 2023 | 10+ min read
A combinatorial approach enabled high-throughput screening of protein libraries for desired target binding.