drug development

Nathalie Fuentes shared her experience of landing a unicorn position in a pharmaceutical company after a postdoctoral fellowship.

Alexander Fleming’s 1928 discovery of a mold with antibacterial properties was only the first serendipitous event on the long road to penicillin as a life-saving drug.

Scientists modified Toxoplasma gondii to deliver a potential Rett Syndrome therapeutic to the mouse brain. 

Inhibiting a protein isoform in the spinal cord alongside morphine improves the opioid’s pain-relieving properties without increasing unwanted side effects.

Kevin Fitzgerald from Alnylam Pharmaceuticals explains the potential of RNA interference for treating disease and highlights recent clinical trial successes.

Advanced microscopy aided in the detection of the pathogen responsible for a nationwide superworm apocalypse and informed the development of a potential vaccine strategy.

Lipid nanoparticles deliver CRISPR tools directly to lung stem cells, offering new therapeutic avenues for treating genetic diseases.

Shapeshifting proteins challenge a long-standing maxim in biology.

An optimized version of prime editing technology raises the possibility of a one-time treatment for cystic fibrosis.

Mesenchymal stem cells with high levels of extracellular vesicle secretion promote vascular regeneration and improve heart function in mice.

Learn how immunotherapy is revolutionizing autoimmune disorder treatment.

Industry expertise helps scientists navigate and streamline antibody-drug conjugate research and development.

Human cells repair RNA breaks induced by a programmable CRISPR system, paving the way for temporary treatments for genetic diseases.

By tinkering with branched mRNA structures, scientists lay the groundwork to build better vaccines in the future.