drug development

A lack of comprehension among some researchers about how to use ClinicalTrials.gov may be hindering public access to trial information and holding up drug study results, an investigation by The Scientist finds.

A large trial adds to a growing list of conditions once thought to be helped by vitamin D supplementation.

Agency members express hope that the availability of a traditional, protein-based vaccine might convince holdouts to get vaccinated.

The biotech company Verve Therapeutics launched the study with the aim of using base editing to treat a genetic condition that causes high cholesterol and increases a person's risk of developing cardiovascular disease.

IgA antibodies appear to bind to specific species of commensal gut bacteria in mice, according to a study.

The shift is likely to add to an ongoing shortage of primates used in labs, which could slow progress in future COVID-19 vaccine development and other areas.

Too often, studies that aim to develop new treatments for patients fail to adequately cite and build upon research that preceded them.

The device can chill nerves as small as a few millimeters across, but more testing and modifications are necessary before it could relieve pain in humans.

The country’s provisional go-ahead could increase pressure already being exerted on the US Food and Drug Administration to approve the therapy.

How scientists aim to induce an immune response against addictive drugs

Researchers are turning to the immune system for help in treating addiction and preventing overdose.

Testing in animals and lab-grown cells suggests the experimental drug could enhance the function of lysosomes within cells.

Human mucus contains glycans that could one day treat harmful Candida albicans infections.

An ear made from the person’s own cells was surgically attached in March, the company behind the technology says.