Leaders of AveXis Out Over Doctored Gene Therapy Data
Leaders of AveXis Out Over Doctored Gene Therapy Data
Novartis, which bought the biotech firm in 2018, announced that the company’s top scientists have left, and news reports say it’s because they were involved in using manipulated data to get the gene therapy Zolgensma approved.
Leaders of AveXis Out Over Doctored Gene Therapy Data
Leaders of AveXis Out Over Doctored Gene Therapy Data

Novartis, which bought the biotech firm in 2018, announced that the company’s top scientists have left, and news reports say it’s because they were involved in using manipulated data to get the gene therapy Zolgensma approved.

Novartis, which bought the biotech firm in 2018, announced that the company’s top scientists have left, and news reports say it’s because they were involved in using manipulated data to get the gene therapy Zolgensma approved.

drug development
First New Tuberculosis Drug Approved in 50 Years
First New Tuberculosis Drug Approved in 50 Years
Jef Akst | Aug 15, 2019
The US Food and Drug Administration green lights a therapy for an extreme form of multidrug resistant TB.
Infographic: Gut Microbes Change How Well Drugs Work
Infographic: Gut Microbes Change How Well Drugs Work
Shawna Williams | Jul 15, 2019
Our resident bacteria can affect the activity of immunotherapies and other medicines in the body.
Table: Personalized Cancer Vaccine Trials in the United States
Table: Personalized Cancer Vaccine Trials in the United States
Jasreet Hundal, Elaine R. Mardis | Jul 15, 2019
There are currently more than two dozen ongoing Phase 1 and Phase 2 trials using different vaccine platforms such as DNA, RNA, synthetic long peptides, and dendritic cells.
How the Microbiome Influences Drug Action
How the Microbiome Influences Drug Action
Shawna Williams | Jul 15, 2019
Through their effects on metabolism and immunity, bacteria in the gut affect whether medications will be effective for a given patient.
Potential Causes of Irreproducibility Revealed
Potential Causes of Irreproducibility Revealed
Abby Olena | Jul 11, 2019
Five independent groups got different results in a drug-response experiment, despite sharing protocols, reagents, and cell lines. The researchers identify technical variables that could be to blame.
Drug Discovery Techniques Open the Door to RNA-targeted Drugs
Drug Discovery Techniques Open the Door to RNA-targeted Drugs
Amber Dance | Jun 1, 2019
New ways to search for druggable RNAs and matching small molecules
MIT Researcher Allegedly Copied Other Groups’ Drug Designs
MIT Researcher Allegedly Copied Other Groups’ Drug Designs
Catherine Offord | May 29, 2019
Executives at a biotech that develops new antibodies argue that Ram Sasisekharan didn’t come up with the structures for at least two experimental therapies that his group has described.
Autism Symptoms May Improve with Modification of Hormone Pathway
Autism Symptoms May Improve with Modification of Hormone Pathway
Catherine Offord | May 2, 2019
Two clinical trials that altered vasopressin signaling report improved social functions in people with autism spectrum disorder, but researchers caution against overinterpreting the results.
Artificial Intelligence Shakes Up Drug Discovery
Artificial Intelligence Shakes Up Drug Discovery
Bianca Nogrady | May 1, 2019
The pharmaceutical industry is looking to machine learning to overcome complex challenges in drug development.