ISTOCK, GEORGEJASON
Microglia Cause Cognitive Decline in Obese Mice
Microglia Cause Cognitive Decline in Obese Mice
The brain’s immune cells gobble up synapses in the hippocampi of rodents fed high-fat or high-sugar diets.
Microglia Cause Cognitive Decline in Obese Mice
Microglia Cause Cognitive Decline in Obese Mice

The brain’s immune cells gobble up synapses in the hippocampi of rodents fed high-fat or high-sugar diets.

The brain’s immune cells gobble up synapses in the hippocampi of rodents fed high-fat or high-sugar diets.

drug development, clinical trials, neuroscience, immunology
Image of the Day: This Little Piggy
Image of the Day: This Little Piggy
Sukanya Charuchandra | Sep 20, 2018
Recordings of electrical activity in porcine brains finds similarities to rodent neural tissue.
Exercise’s Benefits to Dementia Can Be Made Chemically
Exercise’s Benefits to Dementia Can Be Made Chemically
Ruth Williams | Sep 6, 2018
Boosting both neurogenesis and a brain-derived growth factor can mimic the cognitive benefits of exercise in a mouse mode of Alzheimer’s disease.
AACR Apologizes for Delays in Retracting Papers
AACR Apologizes for Delays in Retracting Papers
Catherine Offord | Sep 5, 2018
Nine of the most recent retractions from AACR journals are for papers coauthored by embattled cancer researcher Bharat Aggarwal.
Early Results of First In Vivo Gene-Editing Trial Encouraging
Early Results of First In Vivo Gene-Editing Trial Encouraging
Kerry Grens | Sep 5, 2018
Two patients who received Sangamo’s zinc finger–based treatment for Hunter syndrome have lower biomarkers of the condition, but no signs of new enzyme production.
Adult Cardiac Stem Cells Don’t Exist: Study
Adult Cardiac Stem Cells Don’t Exist: Study
Diana Kwon | Sep 5, 2018
A mouse study adds to the growing body of work disputing the ability of progenitor cells to regenerate muscle tissue in adult mammals’ hearts.
US Companies Launch CRISPR Clinical Trial
US Companies Launch CRISPR Clinical Trial
Catherine Offord | Sep 3, 2018
The Germany-based study will test an ex vivo genome-editing therapy for the inherited blood disorder β-thalassemia.
First iPS Cell Trial for Heart Disease Raises Excitement, Concern
First iPS Cell Trial for Heart Disease Raises Excitement, Concern
Katarina Zimmer | Aug 31, 2018
Without knowing the cells’ mechanism of action, researchers question the best way to administer them to patients.
Infographic: Treating Duchenne Muscular Dystrophy with CRISPR
Infographic: Treating Duchenne Muscular Dystrophy with CRISPR
Sandeep Ravindran | Aug 30, 2018
The disease is caused by mutations in a single gene. Can gene editing fix the problem?
Gene Editing Could One Day Treat Muscle Disorders
Gene Editing Could One Day Treat Muscle Disorders
Sandeep Ravindran | Aug 30, 2018
Scientists race to develop CRISPR therapies that could save the lives of kids with muscle-wasting conditions.