drug development, developmental biology, immunology
Opinion: Label Drugs That Are Tested on Animals
Opinion: Label Drugs That Are Tested on Animals
Shaun Khoo | Jan 16, 2018
Transparency about the role of animals in drug development could help raise awareness of and appreciation for preclinical research.
Researchers Develop a Technique to Regenerate the Mouse Thymus
Researchers Develop a Technique to Regenerate the Mouse Thymus
Jim Daley | Jan 12, 2018
The discovery reveals the role of a growth factor and endothelial cells in thymus repair, and could have implications for chemotherapy and radiation patients’ recovery following treatment.
Image of the Day: See You Later!
Image of the Day: See You Later!
The Scientist Staff | Jan 8, 2018
Developmental biologists take a close look at how alligator embryos grow. 
Maternal Response to Zika Damages Mouse Fetuses
Maternal Response to Zika Damages Mouse Fetuses
Catherine Offord | Jan 5, 2018
Signaling pathways triggered by the mother’s immune system may cause complications during fetal development.
Child Receives Transgenic Skin
Child Receives Transgenic Skin
Ruth Williams | Jan 1, 2018
A combination gene-and-cell therapy has given a boy with a grievous skin disease a new lease on life, and resolved a dermatology debate to boot.
Sex Differences in Opioid Analgesia: A Complicated Picture
Sex Differences in Opioid Analgesia: A Complicated Picture
Catherine Offord | Jan 1, 2018
Researchers are beginning to tease apart the mechanisms underlying differences in how males and females respond to powerful painkillers.
Targeting Sodium Channels for Pain Relief
Targeting Sodium Channels for Pain Relief
Catherine Offord | Jan 1, 2018
The race to develop analgesic drugs that inhibit sodium channel NaV1.7 is revealing a complex sensory role for the protein.
Animal Analgesics
Animal Analgesics
The Scientist Staff | Jan 1, 2018
A cornucopia of toxins in the animal kingdom could provide inspiration for novel painkillers, but so far, effective drugs have proven elusive.
 
Novel Analgesics at a Snail’s Pace
Novel Analgesics at a Snail’s Pace
Bob Grant | Jan 1, 2018
Studying cone snail venom has yielded novel pain pathways, but the peptides that function as toxins are difficult to translate into drugs.
Researchers Mine Centipede Toxins for Analgesics
Researchers Mine Centipede Toxins for Analgesics
Catherine Offord | Jan 1, 2018
Venomous centipedes may harbor a clue to the creation of a successful pain-killing compound for humans.