drug development, disease & medicine, genetics & genomics
Scientists Doubt Results of CRISPR’d Embryos
Scientists Doubt Results of CRISPR’d Embryos
Aggie Mika | Aug 31, 2017
Six scientists question the authors’ conclusions about the DNA repair process that led to the human embryos’ correction of a defective gene.
Global Patterns of Human Epigenetic Variation
Global Patterns of Human Epigenetic Variation
Ashley Yeager | Aug 28, 2017
A study of five far-flung human populations gives clues to adaptations to environmental pressures.
Driving Down Pests
Driving Down Pests
Amy Lewis | Aug 27, 2017
A computer model estimates that gene-drive technology could wipe out populations of an invasive mammal on islands. 
Zika Linked to More Neurological Problems in Adults
Zika Linked to More Neurological Problems in Adults
Kerry Grens | Aug 14, 2017
A review of several dozen hospitalized patients in Brazil finds neurological conditions, including inflammation of the brain and spinal cord, in addition to Guillain-Barre syndrome.
CRISPR Corrects RNA-based Disease Defects
CRISPR Corrects RNA-based Disease Defects
Kerry Grens | Aug 10, 2017
In human cells, researchers deploy the genome editor to snip out toxic repetitive sequences.
Image of the Day: Everybody Needs a Friend
Image of the Day: Everybody Needs a Friend
The Scientist Staff | Aug 10, 2017
The protein encoded by the gene that causes Fragile X in humans partners with another protein, dNab2, to alter gene expression in fruit fly neurons.
A Database of Genetic Differences Among Lab Mice
A Database of Genetic Differences Among Lab Mice
Ashley P. Taylor | Aug 7, 2017
Researchers have catalogued mutations in the coding regions of 36 of the most important mouse strains.
DNA Analysis Throws New Light on the 1845 Franklin Arctic Expedition
DNA Analysis Throws New Light on the 1845 Franklin Arctic Expedition
Catherine Offord | Aug 3, 2017
Anthropologists make use of forensic science to delve into historical mysteries.
Final Nail Hammered into NgAgo Coffin
Final Nail Hammered into NgAgo Coffin
Kerry Grens | Aug 3, 2017
The paper describing the gene-editing method is retracted.
Details Published on CRISPR-treated Embryos
Details Published on CRISPR-treated Embryos
Kerry Grens | Aug 2, 2017
Scientists correct a mutation in fertilized eggs that causes a severe cardiac disease.
Scientists Destroy Entire Chromosome with CRISPR
Scientists Destroy Entire Chromosome with CRISPR
Kerry Grens | Aug 1, 2017
Multiple DNA breaks at either the centromere or the long arm of the mouse Y chromosome cause it to fragment and disappear.
Human Genetic Variation May Complicate CRISPR
Human Genetic Variation May Complicate CRISPR
Ashley Yeager | Jul 31, 2017
Slight sequence differences confound target sites in precision genome-editing, a study shows.
Zebrafish Embryos Survive Deep Freeze and Quick Thaw
Zebrafish Embryos Survive Deep Freeze and Quick Thaw
Ashley Yeager | Jul 28, 2017
In a first, scientists reanimate the fish using embedded gold nanoparticles that heat up cells by absorbing laser light.
Scientists Edit Viable Human Embryos in U.S.
Scientists Edit Viable Human Embryos in U.S.
Kerry Grens | Jul 27, 2017
The embryos, whose genes were altered by CRISPR, were not intended for implantation. 
Massive RNAi Screens Probe for Genes Important to Cancer
Massive RNAi Screens Probe for Genes Important to Cancer
Kerry Grens | Jul 26, 2017
Two freely available databases include data on hundreds of human cancer cell lines. 
Dogs with Duchenne Treated with Gene Therapy
Dogs with Duchenne Treated with Gene Therapy
Diana Kwon | Jul 25, 2017
Researchers restored muscle function in animals with muscular dystrophy.
Dogs’ Friendly Demeanor Written in Their DNA
Dogs’ Friendly Demeanor Written in Their DNA
Bob Grant | Jul 20, 2017
Researchers pinpoint the genes that make pooches so dang affable.
Dogs Have a Single Genetic Origin: Study
Dogs Have a Single Genetic Origin: Study
Diana Kwon | Jul 18, 2017
A new genetic analysis contradicts a 2016 study proposing that our canine companions were domesticated from two distinct populations.
Most of Human Genome Nonfunctional: Study
Most of Human Genome Nonfunctional: Study
Kerry Grens | Jul 17, 2017
An estimate derived from fertility rates concludes that at least 75 percent of our DNA has no critical utility.
Recreating Fish Migration Written Through Environmental Genomics
Recreating Fish Migration Written Through Environmental Genomics
Aggie Mika | Jul 16, 2017
Scientists examine floating traces of DNA left by fish to better understand New York’s aquatic life.