drug development, literature
Condensin Folds DNA Through Loop Extrusion
Condensin Folds DNA Through Loop Extrusion
Diana Kwon | Jun 1, 2018
By observing the activity of a protein complex in real time, researchers have uncovered new evidence for a long-standing theory.
Incomplete Immunity
Incomplete Immunity
Jim Daley | Jun 1, 2018
By combining experimental data with computer models, researchers were able to predict a pathogen’s evolution toward more virulence.
Productivity Paradox
Productivity Paradox
Jim Daley | Jun 1, 2018
During the last ice age, there wasn’t much plant matter to eat on northern steppes, but herbivorous woolly mammoths were abundant. How did they survive?
New Treatments for Phenylketonuria Aim to Loosen Reins on Strict Diet
New Treatments for Phenylketonuria Aim to Loosen Reins on Strict Diet
Diana Kwon | May 29, 2018
Biotechs have developed enzyme replacements and genetically modified probiotics to treat patients with the rare metabolic disorder.
Immunotherapy More Effective in Men: Study
Immunotherapy More Effective in Men: Study
Kerry Grens | May 18, 2018
Women with metastatic cancer who were treated with a checkpoint inhibitor had a smaller benefit than did men.
FDA Approves Drug to Ease Symptoms of Opioid Withdrawal
FDA Approves Drug to Ease Symptoms of Opioid Withdrawal
Catherine Offord | May 17, 2018
Lucemyra is the first non-opioid drug to be approved in the U.S. specifically for this purpose.
Patient Registries to Bolster Cell- and Gene-Therapy Clinical Trial Data
Patient Registries to Bolster Cell- and Gene-Therapy Clinical Trial Data
Anna Azvolinsky | May 15, 2018
As the first personalized cell and gene therapies are approved from small clinical trials, researchers propose the creation of publicly accessible databases to pull together real-world results.  
Researchers Develop a Drug Against the Common Cold
Researchers Develop a Drug Against the Common Cold
Catherine Offord | May 15, 2018
In an in vitro study, the compound completely blocked the replication of rhinoviruses.
Research Scandal Involving Popular Heart Drug Engulfs Three More Papers
Research Scandal Involving Popular Heart Drug Engulfs Three More Papers
Alison McCook, Retraction Watch | May 4, 2018
The scientists involved have hired lawyers to fight the conclusions of a recent investigation into some studies of Diovan in Japan.
Ten-Minute Sabbatical
Ten-Minute Sabbatical
The Scientist Staff | May 1, 2018
Take a break from the bench to puzzle and peruse.