drug development
Getting Drugs Past the Blood-Brain Barrier
Getting Drugs Past the Blood-Brain Barrier
Amanda B. Keener | Nov 1, 2017
To treat neurological disease, researchers develop techniques to bypass or trick the guardian of the central nervous system.
Infographic: Breaking into the Brain
Infographic: Breaking into the Brain
Amanda B. Keener | Oct 31, 2017
The blood-brain barrier is a collection of specialized cells and proteins that control the movement of molecules from the blood to the central nervous system.
Tiny Motors Deliver Ulcer Medication in Mouse Stomachs
Tiny Motors Deliver Ulcer Medication in Mouse Stomachs
Shawna Williams | Aug 17, 2017
The mini machines treated infection somewhat better than antibiotics plus the typical proton pump inhibitor medication. 
CRISPR Corrects RNA-based Disease Defects
CRISPR Corrects RNA-based Disease Defects
Kerry Grens | Aug 10, 2017
In human cells, researchers deploy the genome editor to snip out toxic repetitive sequences.
Chemogenetics Doesn’t Work Like Many Thought
Chemogenetics Doesn’t Work Like Many Thought
Kerry Grens | Aug 4, 2017
A study finds the so-called DREADD method of manipulating neurons using a drug called CNO actually works via clozapine.
Right-to-Try Bill Passes the Senate
Right-to-Try Bill Passes the Senate
Catherine Offord | Aug 4, 2017
The legislation removes restrictions for seriously ill patients to access experimental treatments that have not received FDA approval.
Dogs with Duchenne Treated with Gene Therapy
Dogs with Duchenne Treated with Gene Therapy
Diana Kwon | Jul 25, 2017
Researchers restored muscle function in animals with muscular dystrophy.
Ebola Survivor’s Antibodies Thwart Multiple Viral Strains
Ebola Survivor’s Antibodies Thwart Multiple Viral Strains
Kerry Grens | May 18, 2017
The antibodies bind conserved viral parts, allowing them to neutralize all five Ebola types.
Second-Ever ALS Drug Approved
Second-Ever ALS Drug Approved
Jef Akst | May 8, 2017
Amyotrophic lateral sclerosis patients in the U.S. now have an option besides riluzole, which was approved by the FDA more than two decades ago and only extends life by two or three months.
Infographic: Proteasome Basics
Infographic: Proteasome Basics
John Hines and Craig M. Crews | Apr 30, 2017
The structure and function of the cell's protein-degrading machine